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mass spectrometry resources and products

Mass Spectrometry

Proteins are generally digested with proteases to generate peptides for mass spectrometry analysis (e.g., bottom-up proteomics). Promega provides high quality proteases, including trypsin and alternative proteases specifically developed for mass spec applications. For middle-down proteomics of antibodies, we offer IdeS/IdeZ proteases. We also offer glycosidases for use in analysis of post-translational modifications, as well as peptide reference mixes and other reagents for monitoring mass spec instrument performance.

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Mass Spectrometry Product Groups

Top Mass Spectrometry Products for Your Lab

Mass Spectrometry Basics

Mass spectrometry (MS) is a powerful analytical tool used for proteome-wide analysis and characterization of proteins from a variety of organisms and cell types. MS is a sensitive method for detecting molecules based on their mass-to-charge ratio. Recent advances in mass spectrometry provide tools for protein identification, protein characterization, relative and absolute quantitation, and the study of post-translational modifications and protein:protein interactions.

Mass spec products available from Promega are used for many proteomics research and drug development applications, including identification and characterization of biotherapeutic antibodies and evaluation of post-translational modifications that may affect antibody efficacy or stability.

We offer a complete portfolio of protein analysis products supported by a growing library of educational resources, including technology guides, on-demand webinars, scientific articles and protocols.

Use the links below to learn more about protein analysis products, or to explore learning resources covering topics such as in vitro protein expression, protein purification methods and live-cell protein interaction analysis.