One Enzyme, Endless Capabilities
The small size and bright luminescence of NanoLuc® luciferase bring exquisite sensitivity to many applications. From NanoBRET™ technology, a BRET-based method to study protein:protein and protein:small molecule interactions, to NanoLuc® Binary Technology (NanoBiT), NanoLuc is the cornerstone for studying genetic responses and protein dynamics in cells at physiologically relevant levels. The flexibility of NanoLuc® technologies provides you with the bioluminescent building blocks to understand biological interactions or perform compound screening in ways that have never been possible before.
PROTAC Degradation of Proteins
Learn how to gain more information about the PROTACs you are using to target a protein to the proteasome.
See how to measure protein:protein interactions in real-time at physiological expression levels.
Learn about using bioluminescence to image events in live cells and whole animals—no excitation required.
See how a small reporter that can be packaged without disrupting the virus you are studying to explore viral biology.
Cellular Target Engagement
Study the binding of chemical compounds with target proteins in live cells and determine residence time, cellular affinity and more.
Learn about studying GPCR interactions, specifically β-arrestin recruitment, using a sensitive bioluminescent assay.