NanoLuc® Luciferase
One Enzyme, Endless Capabilities
The small size and bright luminescence of NanoLuc® luciferase bring exquisite sensitivity to many applications. From NanoBRET™ technology, a BRET-based method to study protein:protein and protein:small molecule interactions, to NanoLuc® Binary Technology (NanoBiT), NanoLuc is the cornerstone for studying genetic responses and protein dynamics in cells at physiologically relevant levels. The flexibility of NanoLuc® technologies provides you with the bioluminescent building blocks to understand biological interactions or perform compound screening in ways that have never been possible before.
New to NanoLuc® Technologies? Learn more in this blog post
Explore the Capabilities of NanoLuc® Technologies
Protein:Protein Interactions
See how to measure protein:protein interactions in real-time at physiological expression levels.
Bioluminescence Imaging
Learn about using bioluminescence to image events in live cells and whole animals—no excitation required.
Reporter Viruses
See how a small reporter that can be packaged without disrupting the virus you are studying to explore viral biology.
Cellular Target Engagement
Study the binding of chemical compounds with target proteins in live cells and determine residence time, cellular affinity and more.
GPCR Interactions
Learn about studying GPCR interactions, specifically β-arrestin recruitment, using a sensitive bioluminescent assay.
