Lumit™ Technology: Fast and Easy Immunodetection
Lumit™ Technology enables bioluminescence-based detection of specific antigens or antibodies, simplifying immunoassay protocols and speeding time to results. Based on the award-winning NanoBiT® complementation system, Lumit™ Technology powers sensitive and accurate immunoassays for research and clinical applications.
Lumit™ Immunoassays provide a faster, more reliable alternative to ELISAs, eliminating the variability associated with multiple wash steps, and providing the convenience of a simple and sensitive luminescent detection method. Because of these advantages, Lumit™ Immunoassays are easily adaptable to automation for labs processing large numbers of samples.
Sensitive, Luminescent Analyte Detection
Easy, No-Wash Workflow for Automation-Friendly Analyte Detection
The luminescent detection method of the Lumit™ Immunoassays eliminates the need for the multiple wash steps, and the simple workflow makes the assays easily adaptable for automation.
Lumit™ Immunoassay Options
Pre-built Lumit™ Immunoassays are available for detecting popular targets including cytokines, glucagon, insulin, phosphorylated proteins and neonatal Fc receptor binding. We also offer antibody labeling kits and detection reagents for creating your own assays or our custom team can help you develop your own assay.
DIY Assays
Antibody labeling kit and detection reagents to build your own immunoassays.
Pre-Built Assays
Kits to detect specific targets including cytokines, insulin, glucagon, neonatal fc receptor binding and phosphorylation activity.
Custom Assays
Consult with our team to develop your own Lumit™ application.
Optimize Your Lumit™ Immunoassay Workflow With Support From Our Automation Experts
Our Field Support Specialists are experts in major liquid handler types, including the Promega Maxprep™ System, Hamilton Microlab STAR® series, Tecan Freedom EVO® and Fluent® series, Eppendorf epMotion® and Beckman Biomek® series. We offer prewritten and customized scripts and in-lab/remote assistance. Let us help optimize your current workflow or discuss automation solutions to fit your lab’s needs.
Learn More About Lumit™ Technology with Our Webinar Series
Webinar:
Bioluminescent Analyte Detection with Lumit™ Immunoassays
Webinar:
Using Lumit™ Technology to Address Inflammasome-Mediated Cytokine Release
Webinar:
Advances in Glucagon Detection Supporting Diabetes and Metabolic Disorder Research
Webinar:
Optimizing IL-6 Detection for High-Throughput Screening
Dig Into the Data with These Papers and Posters
Research Paper:
A Homogenous Bioluminescent Assay to Probe Cellular Signaling Pathway Regulation
Poster:
Lumit™ Immunoassays: Bioluminescent, Sensitive, and Homogeneous Analyte Detection Using Labeled Antibodies
Poster:
Lumit™: A Novel Bioluminescent, Homogeneous Immunoassay Platform for Analyte Detection
Research Paper:
Profiling Oncogenic KRAS Mutant Drugs with a Cell-Based Lumit p-ERK Immunoassay
References
- Hall M.P., Unch J., Binkowski B.F., et al. (2012) Engineered luciferase reporter from a deep sea shrimp utilizing a novel imidazopyrazinone substrate. ACS Chem Biol. 7(11), 1848-1857. doi:10.1021/cb3002478
- Dixon A.S., Schwinn M.K, Hall M.P., et al. (2016) NanoLuc Complementation Reporter Optimized for Accurate Measurement of Protein Interactions in Cells. ACS Chem Biol. 11(2), 400-408. doi:10.1021/acschembio.5b00753
- Hwang B.B., Engel L., Goueli S.A., Zegzouti H. (2020) A homogeneous bioluminescent immunoassay to probe cellular signaling pathway regulation. Commun Biol. 3:8. doi:10.1038/s42003-019-0723-9