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Changing stability of key proteins is a primary method of regulation for many signaling pathways. NanoLuc® Luciferase is an ideal fusion partner for monitoring changes in intracellular protein abundance.
The AMP-Glo™ Assay is a homogeneous assay that generates a luminescent signal from any biochemical reaction that produces AMP. This versatile system can measure the activity of a broad range of enzymes.
Obtain better dynamic range and more biologically relevant data with the easy-to-use GloSensor™ assay format for live cell analysis.
Achieve consistent biological responses with highly purified, recombinant growth factors.
A sensitive and easy-to-use assay to measure the activities of GTPases and their associated proteins (i.e., GEFs and GAPs) in vitro.
Simple, "add-mix-measure" luminescent assays for detecting HDAC and Sirtuin enzyme activities.
Count on minimal interference from screening your compound library with luminescent, ATP-based kinase assays. These sensitive and reliable assays are easily scaled to meet your throughput needs.
Follow nuclear receptor pathways with tools ranging from specific expression vectors to cell lines engineered to express your receptor of interest.
Expect more from non-radioactive phosphatase assays that provide the high level of sensitivity and reliability (Z´-factor > 0.7) required for your high-throughput screening studies.