RNA Therapy

Recent technology advancements have led to several approved RNA-based therapies including those using anti-sense oligonucleotides, small non-coding RNA molecules to modulate gene expression or manipulate cellular processes, as well as the use of messenger RNA (mRNA) to express therapeutic proteins.

From research and development through manufacturing, we offer a broad portfolio of products to support your RNA therapy workflow every step of the way.

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mRNA Therapeutics Analysis, Characterization and Manufacturing

From research and development through manufacturing, we offer a broad portfolio of products to support every stage of your mRNA therapeutics development workflow.

DNA Plasmid Creation, Amplification, Purification and Linearization

                                                         mRNA Production and Purification

                                                         Custom and cGMP Manufacturing

RNA Analysis Solutions

Explore solutions for every step of your RNA analysis workflow.


RNA Analysis Workflow




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Reagents for extraction of total RNA and mRNA from blood, cells, tissues and other sample types
Manual Purification Solutions
  • PureYield™, ReliaPrep™ and SV Systems provide a choice of kits for single tube or 96-well-plate-based manual purification of total RNA or miRNA
  • PolyATract® Systems isolate mRNA from total RNA or crude lysates
Maxwell® Instruments
  • Consistent purification in a small, reliable bench-top device
  • Automated purification of 1–48 samples

Automated Nucleic Acid Purification for Liquid Handlers
  • Automated extraction of diverse sample types and volumes
  • Platform-agnostic, customized approach to fit your laboratory's specific needs


RNasin® Ribonuclease Inhibitor
  • Maintains RNase inhibitory activity over a wide temperature range
  • Inhibits a broad spectrum of eukaryotic RNases over a wide pH range (pH 5–8)



QuantiFluor® RNA System



Real-Time PCR
  • Ready-to-use mix using hydrolysis probes or BRYT Green® Dye for higher fluorescence efficiency and less PCR inhibition than SYBR® Green I
  • Multiplex compatible
  • Suitable for automation and high-throughput setup
  • Resistant to a wide range of PCR inhibitors
  • Compatible with both fast and standard cycling methods

Reverse Transcriptase
  • Sensitive transcription of both high-copy and low-copy messages
  • Transcribes short and long transcripts and processes through secondary structure
  • GoScript™ Reverse Transcriptase is available in a variety of formats, from standalone enzymes to mixes and kits


The ProDye™ Terminator Sequencing System provides an improved method of fluorescent Sanger sequencing using a proprietary thermostable DNA polymerase included in the master mix.

  • Simple cycling protocol compatible with a variety of thermal cyclers
  • Designed for a wide range of sequencing applications and maximum read lengths

The Spectrum Compact CE System is an integrated and efficient instrument that brings you the independence to perform Sanger sequencing and fragment analysis in your laboratory, under your control and at your convenience.

  • Sanger sequencing and fragment analysis
  • 32 samples (4 x 8-Well Strip Tubes)
  • 4 Capillaries (36cm)
  • Easy, wizard-like operation and snap-in consumables
  • Integrated, intuitive operational touchscreen

RNAi Screening, siRNA and miRNA Activity

RNA Analysis
Product Information
 siRNA and miRNA Activity

 pmirGLO Dual-Luciferase miRNA Target Expression Vector

 pisCHECK™-2 Vector

 RNAi Screening
 Endogenously Tagged Cell Lines