Sign up for one of our free Webinars to learn about basic and advanced science topics, get tips and techniques for your lab, or find out more about new technologies and products. Webinars cover educational topics in life science research, drug discovery, clinical research, applied sciences, clinical and molecular diagnostics, and more. Live presentations include the opportunity to ask questions via chat. Don't worry if you missed a presentation date—past Webinars are available for on-demand viewing.
A Direct Route to Results: Simplifying Nucleic Acid Workflows with Direct Amplification
Direct nucleic acid amplification from a sample can simplify your workflow and speed your time to results. Join this webinar to learn about new methods and reagents to remove time-consuming nucleic acid extraction steps to prepare your sample for PCR or qPCR amplification and analysis. This simple, fast sample preparation method is cost-effective and can be applied across a variety of sample types such as viruses, FFPE, saliva, blood and plants. Tips and tricks to get the most out of direct amplification approaches will also be discussed.
Melanie Preston, Sr. Applications Scientist, Promega Corporation
Wednesday, June 9, 2021
Antibody-Dependent, Cell-Mediated Killing: HSV and SARS-CoV-2
Vaccine development efforts primarily focus on the generation of neutralizing antibodies that block viral entry, as illustrated by the success of SARS-CoV-2 vaccines. However, this strategy has yielded disappointing results for herpes simplex virus (HSV). This webinar will discuss the role of antibody-dependent cell mediated cytotoxicity (ADCC) and antibody dependent cell-mediated phagocytosis (ADCP) in HSV vaccine development. The webinar will include a live Q&A session.
Betsy C Herold, MD, Professor of Pediatric Infectious Diseases and Microbiology-Immunology, Albert Einstein College of Medicine, New York
Wednesday, June 16, 2021 at 10am CDT / 11am EDT / 4pm London / 5pm Amsterdam-Paris
Thursday, June 17, 2021 at 12pm Singapore / 2pm Sydney / 1pm Seoul / 9:30am New Delhi
NanoBRET™ to Quantify Live Cell Target Engagement at RAS and its Downstream Effectors
Understanding how a small molecule compound interacts with its target protein is essential for developing successful drugs. In vitro measurements of ligand affinity and duration of drug-target interactions (e.g., residence time) often do not translate in vivo. Using the NanoBRET™ Target Engagement (TE) method, we will show the impact of oncogenic KRAS (G12C) on engagement potency for downstream effectors, including BRAF. We have also developed a pan-KRAS NanoBRET™ TE assay and will demonstrate detection of a variety of orthosteric and allosteric engagement mechanisms at this challenging target.
Matthew Robers, PhD, Senior Research Scientist, Promega Corporation
Wednesday, June 23, 2021
Human Gut Microbiome and Cardiometabolic Disease
The gut microbiome, a large and complex community of microorganisms including bacteria, fungi and viruses, has been extensively associated with human health and development of disease. For example, humans with metabolic syndrome and type 2 diabetes (together cardiometabolic disease, CMD), have an altered gut microbiome composition.
In the past years, data suggesting a causal role of the gut microbiome in human disease development have emerged. Dr. Herrema’s group has shown that modulation of the gut microbial composition by fecal microbiota transplantation (FMT) from lean, healthy donors improves insulin sensitivity in insulin resistant recipients. In this webinar, she will provide a bird’s eye view of the role of the gut microbiome, including lessons from FMT in human CMD.
Hilde Herrema, PhD, Medical Biologist, Amsterdam University Medical Centers, Location AMC, Amsterdam, The Netherlands
Wednesday, July 7, 2021 at 9am CDT / 10am EDT / 3pm London / 4pm Amsterdam-Paris
Thursday, July 8, 2021 at 12pm Singapore / 2pm Sydney / 1pm Seoul / 9:30am New Delhi
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