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Genomics
Tuesday, February 13, 2018
Douglas White
Research in circulating cell-free DNA (ccfDNA) has become a key area of interest in the study of normal and disease states. In this first of three ccfDNA webinars, we discuss the history and basics of ccfDNA – what is it, how do laboratories commonly extract ccfDNA, and what are typical applications for ccfDNA?
Genetic Identity
Wednesday, January 31, 2018
Alicia Cadenas and Rachel Oefelein
Forensic science laboratories are facing unprecedented change as more labs are analyzing and reporting DNA mixtures as a likelihood ratio (LR) using probabilistic genotyping software. This webinar covers the progress of probabilistic genotyping from training and implementation to casework results and courtroom experiences.
Cell-Based Assays
Tuesday, January 23, 2018
Matthew Robers, MS
Although a number of extracellular techniques exist to quantitatively measure kinase-ligand binding or inhibition, until now there was no means by which to quantitate target occupancy or drug affinity in live cells. In this webinar we report the use of an energy transfer technique (NanoBRET) in the first quantitative approach to profiling kinase occupancy of a test compound inside live cells.
Genetic Identity
Friday, December 08, 2017
Dr. Ashley Anderson
While no case is without its challenges, medical conditions such as chimerism and genetic outliers (e.g., identical twins) add wrinkles to the analysis and interpretation of the DNA profiles obtained in the case. Medical procedures such as bone marrow transplants can also confuse the results, affecting the legal, social and ethical deliberations of the case. In this webinar, Dr. Anderson will review the interpretation and reporting difficulties experienced when medical conditions have the potential to influence forensic casework results.
MDx
Tuesday, December 05, 2017
Christopher Mason, PhD
Many new methods in genomics enable an integrative, cross-kingdom view of patients (precision metagenomics) and their environment, including metagenome profiles of the world’s cities (MetaSUB.org) and antimicrobial resistance (AMR) markers. In this webinar, technologies that can sequence, quantify, and map nucleic acids will be covered, for Earth and beyond, focusing on methods from Promega that enable these projects and missions.