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Small Molecule Drug Discovery

The process of small molecule drug discovery can be complex and challenging. A typical workflow begins with hit identification and assay development, and carries through to preclinical candidate selection. High-throughput screening of drug candidates plays in essential role in the drug discovery process.

Promega offers a comprehensive selection of tools to accelerate drug discovery, based on an innovative, sensitive bioluminescence platform.

Services

support for cros

Support for CROs

Discover how Promega can help your contract research organization (CRO) develop better solutions for your clients.

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elite acccess services and materials

Small Molecule Profiling and Assay Development

Partner with us to access our latest technologies and materials for drug discovery research and development.

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Drug Discovery Conferences and Tradeshows

Promega scientists will be attending and speaking at key drug discovery conferences and tradeshows throughout the year. Join us to learn more about innovative solutions to accelerate your research.

 

Event Name 2022 Dates Location Presentations
DDR, ATR & PARP Inhibitors Summit January 25-27 Virtual Video Presentation
3rd RAS/MAPK Pathway-Targeted Drug Discovery Summit February 22-24 Virtual Video Presentation
PDF Presentation
2nd Targeted Protein Degradation (TPD) Summit Europe March 15-17 London, UK PDF Presentation
Next Generation Kinase Inhibitors Summit March 29-31 Boston Presentation
DDC (Drug Discovery Chemistry) April 18-21 San Diego PDF Presentation
2nd Ligase Targeting Drug Development Summit April 26-28 Virtual Video Presentation
2nd Induced Proximity-Based Drug Discovery Summit May 11-12 Boston PDF Presentation
4th RAS-Targeted Drug Development Summit September 26-28 Boston PDF Presentation
Induced Proximity Targeting Undruggables - Europe October 11-12 Basel, Switzerland PDF Presentation
5th Targeted Protein Degradation (TPD) Summit October 25-27 Boston PDF Presentation
Gene Therapy Analytical Development November 28-December 1 Boston Presentation
4th Annual Inflammasome Therapeutics Summit November 29-December 1 Boston Presentation
TPD Assay Development & Screening Summit December 6-8 San Diego Presentation

Interested in more information about small-molecule drug discovery?
We can customize a presentation to answer your questions.

Request a Seminar

About Small Molecule Drug Discovery

The pathway from identification of a novel drug candidate to preclinical trials can be complex. From screening compound libraries to measuring the interaction of a compound with its protein targets to examining the effects on cell health, the process of drug discovery relies on rapid, sensitive and high-throughput assays.

Technologies developed by Promega can help streamline the drug discovery process. NanoBRET™ target engagement assays quantitatively measure target occupancy and compound affinity in live cells. A comprehensive collection of CRISPR-edited cell lines and clones with popular targets fused to a small bioluminescent tag, supports these live-cell assays. In addition, these engineered cells are ideal for studying the effects of degrader compounds, such as PROTACs, IMiDs and molecular glues, in real time. Bioluminescence technology also forms the basis for assays to examine signaling pathways in kinase biology and to study oncogenesis, such as the RAS signaling pathway.

Our small molecule drug discovery products and technologies are supported by a range of services, including our partnerships with CROs and early access to the latest research products and technologies through our Elite Access program.