Proteases and Surfactants

Lys-C, Mass Spec Grade, and Lys-N, Mass Spec Grade

Cleavage site: C-terminal or N-terminal of Lys. Optimal pH: 7–9.

VA1170, VA1180

rAsp-N, Mass Spec Grade

Cleavage site: N-terminal of Asp. Optimal pH: 6–9.

VA1160

AccuMAP™ Low pH Protein Digestion Kits

Protein digestion at low (mildly acidic) pH to suppress deamidation and disulfide bond scrambling.

VA1040, VA1050

Rapid Digestion-Trypsin and -Trypsin/Lys-C Kits

Minimize protein digestion time, maximize data output.

VA1060, VA1061

Sequencing Grade Modified Trypsin

Cleavage sites: C-terminal of Arg and Lys. Optimal pH: 7–9.

V5111, V5117, V5113

Mass Spec-Compatible Yeast and Human Protein Extracts

Yeast and human protein extracts for mass spec applications such as instrument monitoring.

V7461, V7341, V6951, V6941

IdeS and IdeZ Proteases

IgG-degrading enzymes that cleave at a single site below the hinge region.

V7511, V7515, V7512, V8341, V8345, V8342

Trypsin/Lys-C Mix, Mass Spec Grade

Cleavage sites: C-terminal of Arg and Lys. Optimal pH: 8.

V5071, V5072, V5073

PNGase F

Catalyzes cleavage of N-linked oligosaccharides between the innermost GlcNAc and asparagine residues.

V4831

Endoglycosidase H

Characterize protein glycosylation in applications such as monitoring protein trafficking and determining glycan location and structure by mass spectrometry.

V4871, V4875

Thermolysin

Cleavage sites: N-terminal of Leu, Phe, Val, Ala, Met, Ile. Optimal pH: 5–8.5.

V4001

Pepsin

Cleavage sites: C-terminal of Phe, Leu, Tyr and Trp. Optimal pH: 1–3.

V1959

Elastase

Cleavage sites: C-terminal of Ala, Val, Ser, Gly, Leu and Ile. Optimal pH: 9.

V1891

Arg-C, Sequencing Grade

Sequencing grade endopeptidase for use alone or in combination with other proteases for protein analysis by mass spectrometry.

V1881

rLys-C, Mass Spec Grade

Cleavage site: C-terminal of Lys. Optimal pH: 8–9.

V1671