Assays to measure markers of inflammation or inflammasome activation include measurement of caspase-1 activity and cytokine release from cells.
The Caspase-Glo® 1 Assay provides a homogeneous, bioluminescent method to selectively measure caspase-1 activity, an essential component of the inflammasome, directly from cells or medium. Lumit™ Cytokine Immunoassays measure cytokines released from cells with a simple no-wash, no-transfer protocol completed in only 70 minutes. The luminescent signal provides good sensitivity and excellent dynamic range, allowing assays to be performed directly on cell culture wells with no dilutions required.
The assays are ideal for multiplexing with additional markers of cell health and for automated high-throughput screening applications.
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