Mass Spectrometry

Proteins are generally digested with proteases to generate peptides for mass spectrometry analysis (e.g., bottom-up proteomics). Promega provides high-quality proteases, including trypsin and alternative proteases specifically developed for mass spectrometry applications. For middle-down proteomics of antibodies, we offer IdeS/IdeZ proteases. We also offer glycosidases for use in analysis of post-translational modifications, as well as peptide reference mixes and other reagents for monitoring mass spectrometry instrument performance.