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ADME-Tox Assays

Luminogenic substrates bring the advantages of bioluminescence to the enzymology researcher studying the absorption, distribution, metabolism or excretion of molecules. Our wide selection of bioluminescent enzyme substrates for proteases and metabolic enzymes such as CYPs and MAO provide powerful tools for ADME-tox screens.

22 Products


Biomarker Detected


P450 Activity Detected


Toxicity Pathway Analysis

Shop all ADME-Tox Assays

P450-Glo™ CYP2B6 Assay and Screening Systems

Measure CYP2B6 activity with this luminescent assay, or choose the screening system for a complete set of reagents.

V8321, V8322, V9781

Cytokine Signaling Pathway Analysis Firefly Luciferase Vectors

Four vectors containing response elements (ISRE, SIE, SBE or STAT5RE) that are used to explore cytokine signaling pathways.

E4041, E3671, E4651, E4141

Stress Signaling Pathway Analysis Firefly Luciferase Vectors

Seven vectors containing different response elements used to explore cellular stress-driven signaling pathways.

E3641, E3651, E3661, E4131, E3751, E4001, E4121

GSH/GSSG-Glo™ Assay

Homogeneous assay to quantify total glutathione and glutathione ratios.

V6611, V6612

Luciferin Detection Reagent

Used with pro-luciferin enzyme substrates, available with or without esterase.

V8921, V8920, V8931, V8930

P450-Glo™ CYP2D6 Assay and Screening Systems

Measure CYP2D6 activity with this luminescent assay, or chose the screening system for a complete set of reagents.

V8891, V8892, V9890

P450-Glo™ CYP2C19 Assay and Screening Systems

Measure CYP2C19 activity with this luminescent assay, or choose the screening system for a complete set of reagents.

V8881, V8882, V9880

P450-Glo™ CYP3A7 Assay System

Measure CYP3A7 activity with this luminescent assay.

V8811, V8812

P450-Glo™ CYP3A4 Assay and Screening Systems

Measure CYP3A4 activity with this luminescence assay, or choose the screening systems for complete sets of reagents.

V8801, V8802, V9920, V9910, V9800, V9001, V8911, V8912, V8901, V8902, V9002

P450-Glo™ CYP2C9 Assay and Screening Systems

Measure CYP2C9 activity with this luminescence assay, or choose the screening system for a complete set of reagents.

V8791, V8792, V9790

P450-Glo™ CYP2C8 Assay System

Measure CYP2C8 activity with this luminescent assay.

V8781, V8782

P450-Glo™ CYP1A2 Assay and Screening Systems

Measure CYP1A2 activity with this luminescent assay, or choose the CYP1A2 screening system for a complete set of reagents.

V8771, V8772, V8421, V8422, V9770

P450-Glo™ CYP1B1 Assay System

Measure CYP1B1 activity with this luminescent assay.

V8761, V8762

P450-Glo™ CYP1A1 Assay System

Measure CYP1A1 activity with this luminescent assay.

V8751, V8752

GSH-Glo™ Glutathione Assay

A luminescent-based assay for the detection and quantification of glutathione (GSH) in cells or in various biological samples

V6911, V6912

Showing 22 of 22 Products