Product Availability Update

Promega Manufacturing and Delivery Systems continue to be fully operational during the COVID-19 outbreak. Our teams are in regular contact with suppliers and distributors worldwide and are taking all steps necessary to address both demands for diagnostic tools and reliable delivery of all products as quickly as possible. Learn more

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Compare RNA Extraction Kits

We offer a range of RNA extraction kits for a variety of target molecules and throughput needs—from manual single-preps to small benchtop or large-scale automated systems. Explore the breadth of our portfolio to discover the right solution for your purification needs. 

Process for Multiple Applications at Any Scale

We have a variety of RNA extraction products grouped here by target molecule, so you can easily find the best RNA extraction kit for your needs. Regardless of sample type, you can expect high yields and high-quality RNA target molecules for use in your downstream applications.

Our products cover a variety of throughput options and processing methods, giving you flexible options. If you are looking to process less than 24 samples at a time, choose from our manual single-prep solutions. If you are looking for an automated solution, our cartridge-based kits for use with Maxwell® Instruments can process up to 48 samples in the same run. We also offer  kits designed for fully automated plate-based processing methods.

Manual Single-Prep Solutions Cartridge-Based
Solutions
Plate-Based
Solutions

Spin, vacuum, or magnetic based methods, typically for processing a few (<24) samples at a time.

Flexible and simple walk-away automated processing with Maxwell® instruments. Process 1 to 48 samples per run.

High throughput solutions for 24, 96, or 384-well plate extractions, compatible with liquid handlers. Learn More >

Compare our RNA extraction kits using the tables below to find the purification solution that is right for you.

Kits by Target Molecule

Total RNA
Kit Summary Product Manual
Prep

<24 samples

Maxwell® 
Kits

0–48 samples

Plate-Based

>96 samples

Input Extraction Time

Walk-away RNA extraction from FFPE samples; ideal for NGS and RT-PCR

Maxwell® RSC RNA FFPE Kit  
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  Up to 2.0mm3 2.5 hours

Walk-away extraction of total RNA from whole blood

Maxwell® RSC simplyRNA Blood Kit  
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  Up to 2.5ml 60 minutes
Walk-away extraction of total RNA from cells Maxwell® RSC simplyRNA Cells Kit  
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  Up to 5x106 cells 60 minutes

Walk-away extraction of total RNA from tissue

Maxwell® RSC simplyRNA Tissue Kit  
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  10 to 20mg 60 minutes

Rapid, spin-based extraction of total RNA from FFPE tissue samples

ReliaPrep™ FFPE Total RNA Miniprep System
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    Up to 2.0mm3 90 minutes

Rapid, spin-based extraction of total RNA from cells with low elution volumes

ReliaPrep™ RNA Cell Miniprep System
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    100 to 5x106 cells 30 minutes

Rapid, spin-based extraction of total RNA from tissue with low elution volumes

ReliaPrep™ RNA Tissue Miniprep System
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    0.25 to 20mg 30 minutes

Midi-scale, spin-based RNA extraction from a wide rande of sample types

PureYield™ RNA Midiprep System
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    Up to 20ml blood or 300mg tissue 90 minutes

Rapid vacuum plate-based extraction of total RNA from tissues and cultured cells; compatible with automated methods

SV 96 Total RNA Isolation System    
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Up to 5x106 cells 30 minutes

Spin- or vacuum-based RNA extraction from a wide variety of sample types

SV Total RNA Isolation System
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    Up to 5x106 cells or 60mg 60 minutes

RNA extraction from whole blood in IVD workflows using Maxwell® CSC Instruments

Maxwell® CSC RNA Blood Kit  
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  Up to2.5ml 60 minutes

RNA extraction from FFPE tissue samples in IVD workflows using Maxwell® CSC Instruments

Maxwell® CSC RNA FFPE Kit  
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  Up to 2.0mm3 50 minutes

Walk-away RNA extraction from many plant tissue types

Maxwell® RSC Plant RNA Kit  
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  Up to 100mg 60 minutes
Messenger RNA (mRNA)
Kit Summary Product Manual
Prep

<24 samples

Maxwell® 
Kits

0–48 samples

Plate-Based

>96 samples

Input Extraction Time

Rapid magnetic isolation of mRNA from 100µg to 5mg of total RNA samples

PolyATtract® mRNA Isolation Systems
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100µg to 5mg total RNA 45 minutes

Large-scale isolation of mRNA from up to 2g of crude cell or tissue lysates

PolyATtract® System 1000
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    5mg to 2g 45 minutes
Micro RNA (miRNA)
Kit Summary Product Manual
Prep

<24 samples

Maxwell® 
Kits

0–48 samples

Plate-Based

>96 samples

Input Extraction Time

Walk-away RNA extraction including miRNA from tissue samples

Maxwell® RSC miRNA Tissue Kit  
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Up to 20mg 90 minutes

Walk-away RNA extraction including miRNA from serum or plasma

Maxwell® RSC miRNA Plasma and Serum Kit  
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  Up to 500µl 70 minutes
Rapid spin-based RNA isolation including miRNA from cell or tissue samples with low elution volumes ReliaPrep™ miRNA Cell and Tissue Miniprep System
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    Up to 1x106 cells or 20mg 40 minutes

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