Functional Bioassays

Reporter bioassays and cell health assays are used to characterize and develop novel monoclonal antibody (mAb)-based therapeutics, cell and gene therapies, vaccines, and RNA therapeutics. This page includes product listings and examples of how functional bioassays are used throughout biologics drug development workflows. 

Bioassays are available to interrogate the following biological functions:

  • Fc effector activity
  • Immune checkpoint modulation
  • T cell retargeting
  • Cytokine and growth factor signaling
  • Tumor antigen-specific cell killing

In addition to the products listed, our Assay Development and Services team can provide personalized solutions for your workflow.

A Multipronged Approach to Biologic Therapeutics

Biologic drug developers employ a rapidly growing range of approaches to the treatment of disease. Understanding a drug’s mechanism of action (MOA) is key to successful development. The use of MOA-based bioassays to measure the potency and stability of drug candidates is critical throughout the drug development workflow.


Viral Vaccine Development

These publications highlight the use of Promega ADCC and ADCP bioassays in viral vaccine and therapeutic research and development.

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Immunotherapeutic Drug Development

These publications highlight use of Promega reporter bioassays for mAb therapeutics, bispecific molecules, T cell therapies, cancer vaccines, and other immunotherapy applications

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Our custom bioassay services can help accelerate your biologic drug development workflow.

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