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category-biologics

Immune Checkpoint Bioassays

Our industry leading bioassays can accelerate your immunotherapy drug development. Whether you’re targeting immune checkpoint co-inhibitory, co-stimulatory, or a combination of receptors, we have assays to meet your needs.

12 Products


Immune Checkpoint Bioassays

Shop all Immune Checkpoint Bioassays

FcγRIIb CHO-K1 Cells

FcγRIIb CHO-K1 Cells function to crosslink co-stimulatory agonist antibodies for CD40, OX40, GITR or 4-1BB.

JA2251, JA2255

4-1BB Bioassay

Measure 4-1BB activation and inhibition through the 4-1BB receptor.

JA2351, JA2355

LAG-3/MHCII Blockade Bioassay

Measure the potency and stability of biologics designed to block the interaction of LAG-3 and MHCII.

JA1111, JA1115

CD40 Bioassay

Measure potency and stability of biologics designed as agonists of the CD40 pathway.

Early Access Immune Checkpoint Co-Inhibitory Bioassays

Bioassays include: BTLA, CD28, CD226/CD155, ICOS, Mouse PD-1/PD-L1, PD-1/PD-L2, TIM-3.

Early Access Immune Checkpoint Combination Bioassays

Bioassays include: PD-1 + 4-1BB, PD-1 + CTLA-4, PD-1 + LAG-3.

Early Access Immune Checkpoint Co-Stimulatory Bioassays

Bioassays include: CD27, CD28, CD40, DR3, GITR, HVEM, ICOS, OX40.

PD-1+TIGIT Combination Bioassay

Characterize biologics designed to block PD-1/PD-L1 and TIGIT/CD155, alone or in combination.

J2211, J2215

TIGIT/CD155 Blockade Bioassay

Measure the potency and stability of biologics designed to block the interaction of TIGIT and CD155.

J2201, J2205

CTLA-4 Blockade Bioassay

Measure potency and stability of biologics designed to block CTLA-4 interaction with its ligands.

JA3001, JA3005

PD-1/PD-L1 Blockade Bioassays

Measure the ability of biologics to block immune checkpoint signals

J1250, J1255, J1252

Bio-Glo™ Luciferase Assay System

Bioluminescent detection reagent qualified for use with bioassays that utilize firefly luciferase.

G7940, G7941

Showing 12 of 12 Products