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P450-Glo™ Screening Systems Technical Bulletin

Instructions for Use of Product(s)
V9770, V9790, V9800, V9880, V9890, V9781, V9910, V9920

Literature # TB340

The P450-Glo™ Screening Systems provide a complete set of reagents for performing luminescent cytochrome P450 assays. The systems include a membrane preparation containing recombinant human cytochrome P450 enzyme, a luminogenic cytochrome P450 substrate appropriate for the enzyme, an NADPH Regeneration System, reaction buffer, Luciferin Detection Reagent and Luciferin-Free Water. The P450-Glo™ Screening Systems are ideal for testing the effects of drugs and new chemical entities on cytochrome P450 enzyme activities.

Summary of Changes
The following change was made to the 10/15 revision of this document:
Section 11.A, Step 7 was revised to make the information provided consistent with Tables 16 and 17.

Printed in USA. Revised 10/15.