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Small Molecule Drug Discovery Workflow

Target Identification and Verification

Reporter assays, fusion proteins and reagents for transfection and purification to help you fully characterize on- and off-target effects of your small molecules of interest and perform mechanism of action studies.

33 Products


Technique

Target Source

Detection Method

Shop all Target Identification and Verification

HaloTag® Technology for Protein Analysis

Custom HaloTag® Vectors, functional ligands and live-cell protein interaction assays.

Luciferase Pathway Reporters

Prebuilt luciferase vectors and cell lines for studying signaling pathways.

Custom Maxwell® HT Automated Nucleic Acid Purification Systems

Customizable DNA and RNA purification chemistries for liquid handlers.

NanoBRET™ Target Engagement BET BRD Assays

Directly measure BET bromodomain-test compound affinity and residence time in live cells.

N2131, N2180, N2130, N2140

NanoBRET™ Target Engagement HDAC Assays

Directly measure HDAC-test compound affinity and residence time in live cells.

N2080, N2081, N2170, N2090

Maxwell® RSC ccfDNA Plasma Kit

Extracts circulating cell-free DNA from plasma or serum using the Maxwell® RSC Instrument.

AS1480

Nano-Glo® Dual-Luciferase Reporter Assay System

Ultra-sensitive detection of firefly and NanoLuc® luciferase activities in a single sample.

N1610, N1620, N1630, N1650, N1521, N1531, N1541, N1551

ONE-Glo™ EX Luciferase Assay System

Improved ONE-Glo™ Assay. Higher sensitivity, long-lived luminescence, more storage options.

E8110, E8120, E8130, E8150

HaloTag® Protein Purification System

Enhanced expression and solubility of recombinant proteins with HaloTag® Ligands.

G6280, G6270

ViaFect™ Transfection Reagent

High-efficiency, low-toxicity transfection of many cell types, including iPS cells.

E4981, E4982

NanoBRET™ Target Engagement Assay Components

For use with NanoBRET™ TE BET BRD and HDAC Assays.

N2150, N2120, N2161, N2160, N2191, E4881

Nano-Glo® Luciferase Assay System

Add-mix-measure assay for NanoLuc® Luciferase with >2 hour half-life in most applications.

N1110, N1120, N1130, N1150

FuGENE® 6 Transfection Reagent

Proven, dependable performance. Best for everyday use with common cell lines.

E2691, E2692, E2693

HaloTag® Mammalian Protein Purification System

Highly pure recombinant protein from mammalian cell cultures, including proteins expressed at low levels.

G6790, G6795, G6799

PureYield™ RNA Midiprep System

Rapid, safe RNA purification from cells, bacteria, blood, yeast, plants and other samples.

Z3740, Z3741

Showing 33 of 33 products

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