Methylation Analysis

Universal Assay for Detecting Methyltransferase Activity

The MTase-Glo™ Methylation Assay is a sensitive, luminescence-based assay that measures the activity of a broad range of methyltransferases, including DNA, protein, RNA and small molecule methyltransferases.

Bisulfite Conversion

The MethylEdge® Bisulfite Conversion System provides an efficient method to rapidly perform bisulfite conversion, giving you more intact, converted DNA for downstream applications.


Improve PCR performance in techniques such as bisulfite-specific PCR with the GoTaq® polymerase family of master mixes.

Methylation-Specific Restriction Enzymes

We offer high-quality, dependable enzymes for cloning and DNA analysis. Promega methylation-specific restriction enzymes include: HpaII, MboI, MspI, and Sau3AI.

Luciferase-Based Methylation Detection

We offer FuGENE® HD transfection reagent and optimized luciferase genes and vectors designed for use in reporter assays. Use these tools to measure methylation status and methylation regulators precisely and with high sensitivity.

Featured Resources