Protein Characterization Tools
Antibodies are large molecules with complex, heterogeneous structures that are often unstable and sensitive to external conditions. Due to their high degree of complexity, the development of antibodies as biologics drugs requires a comprehensive set of highly accurate and robust bioanalytical tools for:
- Characterization of antibodies for drug discovery
- mAb purification
- Peptide mapping
- Measurement of glycosylation
- Analysis of PTM
- mAb internalization
Analytical characterization of biologic drugs is critical during all stages of the drug development workflow. We offer a broad portfolio of bioanalytical tools for antibody purification, internalization, peptide mapping, analysis of glycosylation and post-transcriptional modifications.
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Avoiding Artificial Nonenzymatic PTMs During Peptide Mapping
Learn how sample preparation performed at low pH avoids the introduction of artificial nonenzymatic PTMs during peptide mapping.
Measure Therapeutic Antibody Internalization using pH Sensor Dyes
Learn how pH sensor dyes can be used to characterize the internalization of mAb-based therapeutics.