High Capacity Magne® Streptavidin Beads are magnetic affinity beads with high specificity and high capacity for binding biotinylated antibodies and proteins. The magnetic beads are composed of iron encapsulated by macroporous cellulose, resulting in low nonspecific binding and making them ideal for use with complex biological samples. The beads also have excellent magnetic properties for rapid and efficient capture using a variety of magnetic stands.
High Capacity Magne® Streptavidin Beads are well suited for pharmacokinetics studies of therapeutic antibodies during preclinical studies. For example, biotinylated anti-human IgG bound to the High Capacity Magne® Streptavidin Beads can be used for enrichment of Human IgG from serum or plasma samples of non-primate animals and analyzed using mass spectrometry. The high capacity of the beads enables enrichment of antibodies over a wide concentration range using small amount of beads. Enrichment can be automated for high throughput and scaled up to handle various sample volumes. Cat.# V7820 is provided as a 20% slurry.
Goat Anti-Human Biotinylated IgG is available separately and provided at a concentration of 0.5mg/ml in phosphate-buffered saline (pH 7.4) with 0.1% sodium azide.