Notes: Recombinant leptin was demonstrated to stimulate an increase in cell number of murine yolk sac and fetal liver cells. The authors reported measuring relative cell number using the MTS assay from Promega. (2076)

Notes: The CellTiter^® 96 AQ_ueous Non-Radioactive Cell Proliferation Assay was used to measure the cell survival of wildtype and transfected MDCK cells following detachment from matrix. (0939)

Notes: The CellTiter^® 96 AQueous Non-Radioactive Cell Proliferation Assay was used to measure the mitogenic responsiveness of hematopoietic progenitor (FDC2-ER) cells to erythropoietin (Epo) and stem cell factor (SCF). (2092)

Notes: The CellTiter 96^® AQ_ueous Assay (MTS/PMS) was used to measure the cytotoxicity limits of an antisense oligonucleotide of the TNF receptor I. The highest concentration of oligonucleotide that could be transfected without killing the cells was used for subsequent studies. (0598)

Notes: The MTS-based CellTiter 96^® AQueous One Solution System was used to measure the cytotoxicity limits of an antisense oligonucleotide of the TNF receptor I. The highest concentration of oligonucleotide that could be transfected without killing the cells was used for subsequent studies. (2079)

Notes: Mutant and wildtype arginine vasopressin (AVP) constructs were co-transfected with a CAT-expression vector containing a neo resistance gene. Stable transformants of Neuro2A cells were generated with the aid of the Transfectam^® Reagent and G418 sulfate. CAT activity in stably transfected clones was determined with the CAT Enzyme Assay System. The effect of the mutant AVP constructs on cell viability was determined with the CellTiter 96^® AQ_ueous Cell Proliferation Assay (MTS/PMS). Several constructs displayed marked decreases in cell viability. The cause was necrosis rather than apoptosis due to the absence of DNA laddering and a negative reaction in the Apoptosis Detection System, Fluoroscein (data not shown). The name of the Apoptosis Detection System, Fluorescein, has changed to DeadEnd™ Fluorometric TUNEL System. (1009)

Notes: The MTS-based CellTiter 96^® AQ_ueous Non-Radioactive Cell Proliferation Assay was used to measure the effects of viral infection-induced sensitivity to production of 5-fluorouracil on the human cholangiocarcinoma cell line SK-ChA-1. (2081)

Notes: The CellTiter 96^® AQ_ueous Non-Radioactive Cell Proliferation Assay was used to measure the viability of medulloblastoma cells (+/- human TrkA) cultured in the presence of NGF for four days. (1519)

Notes: The CellTiter 96^® AQueous Non-Radioactive Cell Proliferation Assay (MTS/PMS) was used to measure the cytotoxicity (IC-50 values) of 11 kinase inhibitors on a Jurkat cell line transfected with HCMV enhancer-luciferase reporter construct. (2070)

Notes: The CellTiter 96^® AQ_ueous Non-Radioactive Cell Proliferation Assay was mentioned for determining the viability of prostate epithelial cells to study the balance among various signalling mechanisms of apoptosis. (1731)

Notes: The MTS-based CellTiter 96^® AQ_ueous Non-Radioactive Cell Proliferation Assay was used to measure the effects of anti-STAT, anti-ERK1, and anti-MEK1 antibody electroporation on angiotensin II and PDGF stimulation of rat aortic vascular smooth muscle cells. (2074)

Notes: The CellTiter 96^® AQ_ueous Non-Radioactive Cell Proliferation Assay (MTS/PMS) was used to measure the proliferation of S91 cells. The TNT^® Coupled Reticulocyte Lysate System was used to translate the retinoic acid receptor and the retinoid X receptor. These were then assayed in gel shifts. The recombinant human AP-1 and the AP-1 Consensus Oligonucleotides were used in the gel shift assays as well. (0360)

Notes: The CellTiter 96^® AQueous Non-Radioactive Cell Proliferation Assay was used to measure relative viable cell number of S91 murine melanoma cells. Cells treated for 5 days with different concentrations of various retinoids all showed growth arrest suggesting that retinoic acid receptors (RAR) and retinoid X receptors (RXR), can directly or indirectly inhibit cell proliferation. (1710)

Notes: Overexpression of metallothionein (MT) is linked to decreased cancer survival. One hypothesis is that MT protects from retinoic acid (RA) induced cytotoxicity by scavenging free radicals. This study compared cell viability in two breast cancer cell lines that differ in basal MT expression and estrogen receptor expression. Cells were pretreated with zinc to induce MT expression and then treated with RA. Cell viability was determined using the Cell Titer 96^® AQ_ueous Non-Radioactive Cell Proliferation Assay. (2482)

Notes: The authors measured the in vitro TPO activity of thrombin-cleaved rhTPO in FDCP-2 cells expressing human Mp1 by measuring cell proliferation using the CellTiter 96® AQ_ueous Non-Radioactive Cell Proliferation Assay. (2487)

Notes: The CellTiter 96^® AQueous Non-Radioactive Cell Proliferation Assay was used to measure viability of human umbilical vein endothelial cells (HUVEC) treated with combinations of TNFalpha and VEGF. Viability assays demonstrated that VEGF significantly inhibits apoptosis in TNFalpha-treated HUVEC. (1711)

Notes: The CellTiter 96^® AQueous Non-Radioactive Cell Proliferation Assay was used to quantify the number of viable E8 expressing Jurkat cells (and non-expressing controls) when incubated with recombinant sTRAIL, an orphan member of the TNF family that is structurally similar to the CD95L. (1714)

Notes: The CellTiter 96^® AQ_ueous Non-Radioactive Cell Proliferation Assay was used to measure the effect of expression of the anti-erbB-2 sFv on cell growth kinetics and viability of A549 human lung carcinoma cells. (2120)

Notes: The authors compared MTT (CellTiter 96^® Non-Radioactive Cell Proliferation Assay) and MTS (CellTiter 96^® AQueous Non-Radioactive Cell Proliferation Assay) tetrazolium salts and report that DT-diaphorase inhibitors abolish MTS but not MTT formazan production. The authors conclude that MTT and MTS/menadione resulted in formazan production via a different electron transfer pathway. (2117)

Notes: The CellTiter 96^® AQueous Non-Radioactive Cell Proliferation Assay was used to measure and demonstrate the cytotoxic effects of maltol on mouse Neuro 2a, human IMR 32 neuroblastoma cell lines as well as primary murine fetal hippocampal neuronal cultures. By comparing the results of DNA laddering and TUNEL assays, the authors suggest the toxic effects of maltol is mediated through apoptosis. The correlation of these data suggest that the CellTiter 96^® AQueous Non-Radioactive Cell Proliferation Assay can be used to screen for apoptosis. (2123)

Notes: The system was used to measure and demonstrate the cytotoxic effects of maltol on murine Neuro2A, human IMR32 neuroblastoma and primary murine fetal hippocampal neuronal cultures. By comparing the results of DNA laddering and TUNEL assays, the authors suggest the toxic effects of maltol is mediated through apoptosis. The correlation of these data suggest that the CellTiter 96^® AQ_ueous Assay System can be used to screen for apoptosis. (1562)

Notes: MTS was used to compare growth of rat intestinal epithelial cells plated on collagen I or laminin and stimulated with EGF, IGF-I, TGF alpha and various combinations. (2235)

Notes: CellTiter 96 AQueous Non-Radioactive Cell Proliferation Assay was used to demonstrate that NF2 antisense oligonucleotides significantly increased the number of viable Schwann-like STS26T cells in a proliferation assay. (1564)

Notes: The CellTiter 96^® AQueous Non-Radioactive Cell Proliferation Assay was used to demonstrate that NF2 antisense oligonucleotides significantly increased the number of viable Schwann-like STS26T cells in proliferation assays. (2089)

Notes: The CellTiter 96^® AQueous Non-Radioactive Cell Proliferation Assay was used to quantitate viable cells in co-culture experiments to determine the inhibition of Mo-dependent T cell apoptosis by anti-Fas and other factors. (1721)