T Cell Activation Bioassay (IL-2), Propagation Model Technical Manual
Instructions for Use of Product(s)
J1631
Literature # TM491
The T Cell Activation Bioassay (IL-2), Propagation Model, is a bioluminescent cell-based assay that overcomes the limitations of existing assays and can be used for the discovery and development of novel biologic and cell therapies aimed at inducing, strengthening and/or engineering T cell responses. The assay consists of a genetically engineered Jurkat T cell line that expresses a luciferase reporter driven by an IL-2 promoter. The TCR/CD3 Effector Cells (IL-2) are provided in Cell Propagation Model (CPM) format, which includes cryopreserved cells that can be thawed, propagated and banked for long-term use.
Summary of Changes
The following change was made to the 3/19 revision of this document:
1. Corrected the HyClone fetal bovine serum catalog number in Section 3.A.
Revised 3/19