Innate Pharma develops therapeutic antibodies and part of the workflow requires processing many samples. They needed an automated process for plasmid preps that would work on a Tecan EVO system. In order to effectively transfect cells, the plasmid purification needed to be developed at a midiprep scale.
Our team helped the customer develop a protocol for their Tecan EVO 200 system that could automate plasmid preps from 30ml of bacterial culture and provide a return of >100μg of plasmid. After testing plasmid samples in the workflow, all of Innate Pharma’s criteria were met and the solution became part of their workflow.