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Caspase Inhibitor Z-VAD-FMK

A Cell-Permeant Pan Caspase Inhibitor of Apoptosis

  • Irreversibly binds to catalytic site of caspase proteases
  • Provided in DMSO for convenient addition to cell culture or extracts

Size

Catalog number selected: G7231

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Caspase Inhibitor Z-VAD-FMK
50μl
$ 305.00
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Z-VAD-FMK (carbobenzoxy-valyl-alanyl-aspartyl-[O-methyl]- fluoromethylketone) is a cell-permeant pan caspase inhibitor that irreversibly binds to the catalytic site of caspase proteases and can inhibit induction of apoptosis. For inhibition of apoptosis, Z-VAD-FMK should be added at the same time that apoptosis is induced. Z-VAD-FMK is provided at 20mM in DMSO for convenient addition to cell culture or extracts. The peptide is O-methylated in the P1 position on aspartic acid, providing enhanced stability and increased cell permeability. The suggested concentration for use in the anti-Fas mAb-treated Jurkat cell culture model system is 20μM.


For more information, see the Protocols & Applications Guide.

Specifications

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Item Part # Size

Caspase Inhibitor Z-VAD-FMK

G723B 1 × 50μl

SDS

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Use Restrictions

For Research Use Only. Not for Use in Diagnostic Procedures.

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Specifications

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Item Part # Size

Caspase Inhibitor, Z-VAD-FMK

G723A 1 × 125μl

SDS

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Certificate of Analysis

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For Research Use Only. Not for Use in Diagnostic Procedures.

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