Notes: In this paper, cytotoxicity results obtained using an MTT-based assay were confirmed using the CellTiter-96^® AQ_ueous Non-Radioactive Cell Proliferation Assay and the CellTiter-Glo™ Luminescent Cell Viability Assay on primary human vaginal keratinocyte cultures and immortalized VK2/E6E7 cells. (2605)

Notes: This study explores the utility of indirect cell viability measurements based on metabolic activity for monitoring neural stem/progenitor cells. The tetrazolium salt WTS-8 and the CellTiter-Glo^® Luminescent Cell Viability Assay were compared to BrdU incorporation for their ability to monitor cell proliferation. The authors conclude that both WTS-8 and CellTiter-Glo^® can accurately monitor cell proliferation, but that the increased sensitivity and ease-of-use of CellTiter-Glo^® assay made it an ideal choice for this application. (3123)

Notes: In this paper, cell proliferation assays were performed on 22Rv1 cells (human prostate tumor cells) using the CellTiter-Glo™ Luminescent Cell Viability Assay.  Cells were plated at the appropriate density (10,000 cells/well) in a 24-well multiwell plate. Twenty-four hours after plating, cells were exposed to various concentrations of CHS 828 for 24 h. DMSO in PBS was used as a solvent control. After treatment, the medium was removed and replaced with 200 μl of drug-free medium, and cells were incubated further for 48 h. For detection of the luminescent signal, CellTiter-Glo™ reagent was added, and light was measured in the Wallac 1420 Victor, a multilabel, multitask plate counter. (2606)