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Bioluminescence Imaging of Live Trout for Virus Detection using EnduRen™ Live Cell Substrate

Kari Kenefick
Promega Corporation
Publication Date: 2007


We review a novel method for bioluminescence imaging of live fish. In order to study the entry route and pathogenesis of a member of the virus family Rhabdoviridae in young trout, Harmache et al. used a unique live fish imaging system and bioluminescence. They were able to show locations of viral entry and replication by examining fish at various times postinfection and using a variety of pathogenic and nonpathogenic Novirhabdoviridae isolates.

Promega Notes 95, 25–26.