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Maxwell® RSC ccfDNA Plasma Kit

Maxwell RSC ccfDNA Plasma Kit 48 preps
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Automated ccfDNA Purification with a Simple Three-Step Protocol

  • Purifies circulating cell-free DNA from up to 1ml of plasma
  • Consistently high yields of amplifiable ccfDNA
  • Simple, three-step protocol with no preprocessing


Catalog number selected: AS1480

$ 753.00
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Maxwell® RSC ccfDNA Plasma Kit
48 preps
$ 753.00
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Easy-to-Use Protocol Yields High-Quality, Amplifiable ccfDNA

The Maxwell® RSC ccfDNA Plasma Kit is used with the Maxwell® RSC Instruments to purify circulating cell-free DNA (ccfDNA) or circulating tumor DNA (ctDNA) from 0.2–1.0ml plasma samples. The Maxwell® RSC Instrument processes from 1 to 16 samples, and the Maxwell® RSC 48 Instrument processes from 1 to 48 samples, in approximately 70 minutes. The kit contains everything necessary for purification, with no preprocessing required.  You simply add the plasma samples to the prepared cartridges and press Start. The Maxwell® RSC ccfDNA Plasma Kit is also compatible for use on the Maxwell® CSC Instrument in RUO Mode.

The purified cell-free DNA is of high-quality with little genomic DNA contamination, and is ready for use in downstream applications such as qPCR, next generation sequencing and digital PCR.

No Clogging Worries with a Paramagnetic Particle Mover

Because the Maxwell® RSC instruments are magnetic particle movers, not liquid handlers, they offer advantages over other automated systems. There is minimal risk of cross-contamination because no liquid handling or splashing happens during sample processing. With no clogs and fewer breakdowns, there are fewer disruptions to your workflow.

Simple Three-Step Protocol

The prefilled cartridges and absence of preprocessing steps makes it easy to purify high-quality ccfDNA with a simple three step protocol. In contrast, the lengthy Qiagen protocol requires multiple complicated processing steps.

Simple protocol for cell free DNA or ctDNA extraction from plasma

Simple Protocol saves time. Side-by-side comparison of the protocol steps for the Maxwell® RSC ccfDNA Plasma Kit and the QIAamp® Circulating Nucleic Acid Protocol.

High Yields of amplifiable DNA lets you move to downstream assays quickly

High-Quality ccfDNA is ready-to-use in downstream assays including digital PCR and NGS. 

Comparison of cell free DNA yields with Maxwell RSC ccfDNA plasma kit

Circulating cell-free DNA yields are equivalent to those from the QIAmp® Kit. DNA was purified from 1ml of plasma using the Maxwell® RSC ccfDNA Plasma Kit and the Qiagen QIAmp® Circulating Nucleic Acid Kit. Isolated ccfDNA was eluted in 80µl and yield was quantified by qPCR.


What's in the box?

Item Part # Size Available Separately

Maxwell® RSC Cartridge (RSCG)

AS148A 48 × 1 each

Elution Tubes (0.5ml)

AS620A 1 × 50/pk View Product

Elution Buffer

MC139B 1 × 20ml

RSC Plungers

AS1670 1 × 48/pack View Product


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Certificate of Analysis

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Use Restrictions

For Research Use Only. Not for Use in Diagnostic Procedures.

Storage Conditions


Patents and Disclaimers

U.S. Pat. No. 6,855,499 and other patents.

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