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Coelenterazines

  • 95% pure
  • Supplied as a dried substrate for easy preparation in methanol or ethanol

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Catalog number selected: S2001

$ 129.00 Your price: Log in

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Coelenterazines
Coelenterazine/250µg
$ 129.00
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Luciferases from Renilla, Aequorea and other marine organisms are commonly used as indicators or reporters for studying cellular phenomena in expression assays in eukaryotic cells. Renilla luciferase is often used as a reporter of transcription regulation, whereas apoaequorin is often used as a calcium indicator. Other uses of coelenterazines include chemiluminescent detection of Reactive Oxygen Species (ROS) in cells or tissues. We offer the following coelenterazine analogs:

Coelenterazine (native) is the luminescent substrate for Renilla luciferase and apoaequorin. Formula: C26H21N3O3. Formula Weight: 423.5. Form: Film.

Coelenterazine-h imparts a luminescent intensity with its aequorin complex that is reported to be 10–20 times higher than that of native coelenterazine, making this derivative a useful tool for measuring small changes in Ca2+ concentrations. Formula: C26H21N3O2. Formula Weight: 407.5. Form: Film.

Learn more about custom options for this product at: www.promega.com/custom/

References

  1. Inouye, S. et al. (1997) Biochem. and Biophys. Res. Comm. 233, 349–53.
  2. Blanpain, C. et al. (2001) J. Biol. Chem. 276, 23795–804.
  3. Shimomura, O. et al. (1989) Biochem. J. 261, 913–20.

Specifications

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Item Part # Size

Coelenterazine

S200A 1 × 250μg

SDS

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For Research Use Only. Not for Use in Diagnostic Procedures.

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Specifications

You are viewing: S2011 Change Configuration

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Item Part # Size

Coelenterazine-h

S201A 1 × 250μg

SDS

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Certificate of Analysis

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For Research Use Only. Not for Use in Diagnostic Procedures.

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