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The Heat Is On!

Watch as we talk science with the experts while indulging in blazing hot culinary creations.

Episode 4 Is Here!

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Episode 4: Functional Bioassays

We're back with all new sauces and a hot topic to discuss. Senior Research Scientist and Bioassay Group leader Jamie Grailer talks functional bioassays, the development of assays like TIGIT, LAG3 and thaw-and-use, as well as the biology of homebrewing!

Chapters:

  • 01:12 Fired up on Functional Bioassays
  • 04:51 TIGIT, LAG3 and Thaw 'N Use - Oh My!
  • 08:45 The Biochemistry of Brewing
  • 11:19 Hot Targets in the Works
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New assay development, modification of existing assays, bioassay optimization and qualification, biologic drug profiling and custom cell manufacturing.

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Episode 3: Measuring Targeted Protein Degradation

We're back with all new sauces and a hot topic to discuss. Senior Research Scientist Kristin Riching talks Targeted Protein Degradation, Tailored R&D Solutions and the importance of breaking barriers in STEM for our future scientists. PLUS a bonus appearance from Kristin's African grey parrot, Mister Bird!

Chapters:

  • 1:05 What is TPD?
  • 5:45 Mouth-Melting Methods of Degradation
  • 9:22 Breaking Barriers (And a Sweat!)
  • 15:27 Spicy R&D Solutions

Episode 2: Lumit™ Technology

Senior Research Scientist Hicham Zegzouti takes the hot seat to talk about Promega's Lumit™ Technology. In this episode, we learn about the many applications of Lumit™ immunoassays while Hicham takes on our five spiciest sauces.

Chapters:

  • 1:32 Let's Talk Lumit™
  • 4:23 Hicham Talks Harissa and Application Methods
  • 9:08 Spicy Cell Signaling and Peppery Pathway Activation (Too Much?)
  • 13:53 Gimme More Lumit™
  • 17:41 Hottest Peppers for Protein:Protein Interaction

Episode 1: Target Engagement ​

We connected with Matt Robers, Ph.D., a Senior R&D Scientist at Promega Corporation who specializes in cellular target engagement. Ever wonder how hot peppers cause the heat? In this episode we will dive into the science behind the reaction as well as learn about target engagement technology and the hottest targets right now.

Chapters:

  • 2:00 A Mild Intro to Target Engagement
  • 4:24 Slightly Spicy Ras Targets
  • 7:20 The Body's Reaction to Heat
  • 10:50 Hot TE Services from Elite Access
  • 15:05 Latest Research (Caution: Contents HOT!)