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Maxwell® RSC ccfDNA Plasma Kit

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Automated ccfDNA Purification with a Simple Three- or Five-Step Protocol

  • Purifies circulating cell-free DNA from up to 8ml or more of plasma
  • Consistently high yields of amplifiable ccfDNA
  • Simple, three- or five-step protocol with minimal preprocessing

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Maxwell® RSC ccfDNA Plasma Kit
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Easy-to-Use Protocols Yield High-Quality, Amplifiable ccfDNA

The Maxwell® RSC ccfDNA Plasma Kits are used with Maxwell® RSC Instruments to purify circulating cell-free DNA (ccfDNA) or circulating tumor DNA (ctDNA) from 0.2–1.0ml plasma samples or 2–8ml of plasma. The Maxwell® RSC Instrument processes from 1 to 16 samples, and the Maxwell® RSC 48 Instrument processes from 1 to 48 samples, in approximately 70 minutes. The kit contains everything necessary for purification, with minimal preprocessing required. The Maxwell® RSC ccfDNA Plasma Kits are also compatible for use on the Maxwell® CSC Instrument in RUO Mode.

The purified cell-free DNA is of high quality with little genomic DNA contamination and is ready for use in downstream applications such as qPCR, next-generation sequencing (NGS) and digital PCR.

No Clogging Worries with a Paramagnetic Particle Mover

Because the Maxwell® RSC instruments are magnetic particle movers, not liquid handlers, they offer advantages over other automated systems. There is minimal risk of cross-contamination because no liquid handling or splashing happens during sample processing. With no clogs and fewer breakdowns, there are fewer disruptions to your workflow.

Process Large-Volume Plasma with Minimal User Intervention

Simple Processing Protocol

The prefilled cartridges and absence of preprocessing steps make it easy to purify high-quality ccfDNA with a simple three- or five-step protocol. In contrast, the lengthy Qiagen protocol requires multiple complicated processing steps.

Simple protocol for cell-free DNA and ctDNA extraction 17935ma-w

Simple protocol saves time. Side-by-side comparison of the protocol steps for the Maxwell® RSC ccfDNA Plasma Kits and the QIAamp® Circulating Nucleic Acid Kit.


High Yields of Amplifiable DNA Let You Move to Downstream Assays Quickly

High-quality ccfDNA is ready-to-use in downstream assays including digital PCR and NGS. 

Comparison of cell free DNA yields with Maxwell RSC ccfDNA plasma kit

Circulating cell-free DNA yields are equivalent to those from the QIAamp® Kit. DNA was purified from 1ml of plasma using the Maxwell® RSC ccfDNA Plasma Kit and the Qiagen QIAamp® Circulating Nucleic Acid Kit. Isolated ccfDNA was eluted in 80µl, and yield was quantified by qPCR.

Specifications

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What's in the box?

Item Part # Size Available Separately

Maxwell® RSC Cartridge (RSCG)

AS148A 48 × 1 each

Elution Tubes (0.5ml)

AS620A 1 × 50/pk View Product

Elution Buffer

MC139B 1 × 20ml

RSC Plungers

AS1670 1 × 48/pack View Product

Certificate of Analysis

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Use Restrictions

For Research Use Only. Not for Use in Diagnostic Procedures.

Storage Conditions

DD

Patents and Disclaimers

U.S. Pat. No. 6,855,499 and other patents.

Specifications

You are viewing: AS1840 Change Configuration

What's in the box?

Item Part # Size Available Separately

RSC Plungers

AS1670 1 × 48/pack View Product

Maxwell® RSC Cartridge (RSCP)

AS184A 48 × 1 each

Elution Tubes (0.5ml)

AS620A 1 × 50/pk View Product

Binding Buffer (BBC)

MC1361 1 × 200ml View Product

Maxwell® Resin E

MC148A 1 × 10ml

PCR Elution Buffer (EBE)

MC1511 1 × 5ml View Product

NGS Elution Buffer (EBF)

MC1521 1 × 5ml View Product

Certificate of Analysis

Search by lot number

Use Restrictions

For Research Use Only. Not for Use in Diagnostic Procedures.

Storage Conditions

DD

Patents and Disclaimers

U.S. Pat. No. 6,855,499 and other patents.

U.S. Pat. No. 7,329,488 and S. Korean Pat. No. 100483684.

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