The inflammasome, including the NLRP3 inflammasome, is implicated in a wide variety of chronic inflammatory conditions, including Alzheimer’s disease, inflammatory bowel disease and nonalcoholic steatohepatitis, making it a promising target for therapeutic treatment. Inflammasomes are found in cells of the innate immune system where they play a key role in the inflammatory response. Drugs to inhibit or activate the inflammasome are sought by drug discovery efforts globally.
Watch this 20-minute webinar to understand the assay performance, along with specific examples from each assay. Concordance of results from the three assays with a NLRP3 inflammasome inhibitor is demonstrated.
Martha O'Brien, PhD
Senior Research Scientist
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