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Human Sample Identification and Mixed Sample Analysis Using the GenePrint® 24 System: A Spectrum Compact CE System Application Note

Abstract

Human sample identification is an essential element of many research projects employing human cells, tissues, or mixtures. Identification may be required to track and confirm sample provenance for databasing, biobanking, or research purposes. For example, archival tumor/normal specimen pairs may be tested to confirm they are derived from the same individual.

This study aims to demonstrate the utility of the Spectrum Compact CE System paired with the GenePrint® 24 System for human identification by focusing on the more sensitive application of human mixture analysis. We demonstrate that the Spectrum Compact CE System can be used for detection of low-level human contributors in mixed samples.