Maxwell® RSC XtractAll FFPE DNA/RNA Kit Technical Manual
Instructions for Use of Product(s)
AS1570
Literature # TM762
The Maxwell® RSC XtractAll FFPE DNA/RNA Kit is used in combination with the Maxwell® Instruments specified in the technical manual to provide an easy method for efficient, automated extraction of DNA, RNA or total nucleic acid, or sequential DNA and RNA from formalin-fixed, paraffin-embedded (FFPE) tissue samples. The Maxwell® RSC Instruments are designed for use with predispensed reagent cartridges and additional reagents supplied in the kit with preprogrammed extraction methods, thereby maximizing simplicity and convenience. The Maxwell® RSC Instruments can process from one to the maximum number of samples allowed in an efficient manner with DNA, RNA and total nucleic acid (TNA) samples being extracted in approximately 30 minutes and sequential DNA and RNA extractions in less than 1 hour. Extracted DNA, RNA or total nucleic acid can be used directly in downstream amplification-based assays.
Summary of Changes
The following changes were made to the 7/25 revision of this document:
1. Updated the recommended software version for the Maxwell® RSC 48 or CSC 48 (RUO mode) from version 4.1.0 to new software version 4.1.1 on the cover page and in Section 5.
2. Corrected a subsection heading on p. 12 from 6.E to 4.E.
3. Added warning text to Sections 4.E and 8, noting that the “Sanitation after extraction” setting must be set to OFF before running XtractAll FFPE DNA (Sequential) extraction method, to avoid exposing samples to UV light.
Revised 7/25.