CC1 pan-Kinase Inhibitor

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For use as a control in the NanoBRET® Target Engagement Intracellular Kinase Assays

  • Potent inhibitor to numerous kinases
  • For use with NanoBRET® Target Engagement Intracellular Kinase Assays


Catalog number selected: N2661

$ 285.00
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CC1 pan-Kinase Inhibitor
$ 285.00
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The CC1 pan-Kinase Inhibitor is a chemically synthesized compound that broadly binds to kinases, as determined using the NanoBRET® Target Engagement (TE) Intracellular Kinase Assays. Using these assays, intracellular binding of this product is potent to numerous kinases including but not limited to ITK, NUAK1 and LRRK2, which produced 100% binding inhibition at 300nM. Representative IC50 data of this product for HIPK3 and SBK3 in NanoBRET® TE Intracellular Kinase Assays is reported in Application Notes for NanoLuc®-HIPK3 (NV3231) and NanoLuc®-SBK3 (NV4211) fusion vectors, respectively.

Protocols using the CC1 pan-Kinase Inhibitor can be found in #TM598 and #TM603.

CC1 pan-kinase Inhibitor apparent cellular affinity for HIPK3 & SBK3.
CC1 pan-kinase Inhibitor apparent cellular affinity for HIPK3 & SBK3 determined via NanoBRET® TE Intracellular Kinase Assays. HEK293 cells were transfected with NanoLuc®-HIPK3 Fusion vector (A) or NanoLuc®-SBK3 Fusion vector (B). To determine the apparent cellular affinity of CC1 pan-Kinase Inhibitor the Adherent method detailed in the NanoBRET® TE Intracellular Kinase Assay Technical Manual #TM598 was followed. The recommended NanoBRET® Tracer K-10 concentrations of 1µM for HIPK3 and 0.5µM for SBK were used.

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Item Part # Size Concentration

CC1 pan-Kinase Inhibitor

N266A 1 × 100μl 20mM

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Use Restrictions

For Research Use Only. Not for Use in Diagnostic Procedures.

Storage Conditions


Patents and Disclaimers

CC1 pan-Kinase Inhibitor Limited Use Label License

BY USE OF THIS PRODUCT, RESEARCHER AGREES TO BE BOUND BY THE TERMS OF THIS LIMITED USE LABEL LICENSE. If researcher is not willing to accept the terms of this label license, and the product is unused, Promega will accept return of the unused product and provide researcher with a full refund.
Researcher may use this product for research use only; no transfer or commercial use of this product is allowed. Commercial use means any and all uses of this product by a party in exchange for consideration, including, but not limited to (1) use in further product manufacture; (2) use in provision of services, information or data; and (3) resale of the product, whether or not such product is resold for use in research. Researcher shall have no right to modify or otherwise create variations or derivatives of the product. No other use of this product is authorized without the prior express written consent of Promega.
With respect to any uses outside this label license, including any diagnostic, therapeutic, prophylactic or commercial uses, please contact Promega for supply and licensing information. PROMEGA MAKES NO REPRESENTATIONS OR WARRANTIES OF ANY KIND, EITHER EXPRESSED OR IMPLIED, INCLUDING FOR MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE, WITH REGARD TO THE PRODUCT. The terms of this label license shall be governed under the laws of the State of Wisconsin, USA.

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