Biomarker Discovery

Biomarkers are used to measure cancer risk and indicate the presence of a tumor in a tissue. They reflect the molecular mechanisms driving the development of a tumor and could be used to influence treatment decisions. Circulating cell-free DNA (ccfDNA) has received recent attention as a promising biomarker present in blood plasma.

Circulating Cell-Free DNA

ccfDNA is an important biomarker for certain tumors. The quantity and sequences of ccfDNA molecules found in plasma can indicate the presence of a tumor and offer valuable insights into its characteristics.


ccfDNA 101

Research in circulating cell-free DNA (ccfDNA) has become a key area of interest in the study of normal and disease states. In this webinar, Promega scientist Douglas White discusses the history and basics of ccfDNA, such as: 

  • What is it?
  • How do laboratories commonly extract ccfDNA?
  • What are typical applications for ccfDNA?
View the Webinar

Biopsy in a Tube

Read more about the promises of ccfDNA research.

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ccfDNA Purification from Plasma

With such small, precious samples, it's important to purify high-quality, amplifiable DNA.

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