Biologics Resources
Find information about our functional bioassays for biologic drug discovery. View scientific presentations and posters with the latest technology and data to help with your research needs.
Join us at these virtual events to learn more about our latest Biologics products and applications:
BEBPA US, March 22-25
CASSS Bioassays, April 19-23
AACR, April 10-15, May 17-21
PEGS Boston, May 11-13
TCR Based Therapies Summit, June 8-10
See lists of peer-reviewed publications that used our reporter bioassays for viral vaccine research and immunotherapy drug development assays including mAb therapeutics, bispecific antibodies, oncolytic virus therapy, cancer vaccines, gene therapy and biosimilars.
Scientific Posters
Developing a Bioluminescent PBMC ADCC Assay for the Discovery and Characterization of Therapeutic Antibodies
Presented by Jey Cheng, Sr. Research Scientist
Cell-Based Reporter Bioassays for Development of Fc-Functional and Fc-Silent SIRPa/CD47 Checkpoint Inhibitors
Presented by Jamison Grailer, Sr Research Scientist
Quantitative Cell-Based Bioassays to Advance Immunotherapy Programs Targeting Immune Checkpoint Receptors
Presented by Jamison Grailer, Sr Research Scientist
A No-Wash, Rapid FcRn Binding Immunoassay to Guide the Design and Development of Antibody Therapeutics
Presented by Jeff Nelson, Product Manager
New Products
PBMC ADCC Bioassay
Perform your ADCC method bridging studies with the new PBMC ADCC Bioassay, featuring pre-qualified PBMCs. The assay offers improved consistency and robustness for measuring ADCC. Each assay includes ADCC-qualified PBMC effector cells and a choice of popular target cells expressing a HiBiT fusion protein. The simple, add-mix-read format uses bioluminescent detection for maximum sensitivity.
Lumit™ Immunoassays
Replace conventional immunoassays, such as Western blots and ELISAs, with new Lumit™ Immunoassays. These assays offer direct luminescence measurement in cell culture, broad dynamic range, and can be completed in as little as 30 minutes.
Lumit™ Immunoassays are available for a range of applications, including protein phosphorylation and pathway analysis, FcRn binding, cytokine detection, metabolite research, and more. You can also build your own Lumit™ immunoassays with our labeling and detection kits.
Learn More
General principle of a Lumit™ Immunoassay. Antibodies are chemically labeled with the small and large subunits of NanoLuc® Luciferase, known as SmBiT and LgBiT, respectively. In the presence of an analyte, the two antibodies come into close proximity, allowing SmBiT and LgBiT to form an active enzyme and generate a bright luminescence signal.
Webinars
Bioanalytical Tools for Biosimilar Development
Learn about functional bioassays and protein characterization reagents to optimize your biosimilar drug development workflow.
Tips and Tools for Successful Immunotherapy Bioassay Development
Our bioassay experts answer your questions about the design, selection and optimization of MOA-based bioassays.
Rapid Antibody Selection Methods for Immunotherapeutic Candidate Development
Learn about time- and cost-saving strategies for selecting antibodies against immunotherapy targets.