Poon, H., Elliott, J., Modler, J. and Frégeau, C.
Notes: The authors attempted to isolate DNA from samples tested with Hemastix® reagent strips, which are commonly used to test for the presence of blood, using the DNA IQ™ System. Yields from samples that had been tested with Hemastix® strips were dramatically lower than those from untested samples. The experiments suggested that 3,3´,5,5´tetramethylbenzidine (TMB) irreversibly binds to the magnetic DNA IQ™ Resin to prevent DNA recovery. To circumvent this, the authors implemented an effective indirect screening method, where the unknown sample was rubbed with dry filter paper, which was then tested with a prewetted Hemastix® strip. (4035)