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Citations Search

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7, 186–199. Dysfunctional BMPR2 signaling drives an abnormal endothelial requirement for glutamine in pulmonary arterial hypertension 2017

Egnatchik, R. A., Brittain, E. L., Shah, A. T., Fares, W. H., Ford, H. J., Monahan, K. and Nguyen, T. T.

Notes: In this paper, researchers used the SIRT-Glo™ Assay to measure purified recombinant human SIRT3 activity.  (4862)

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Am. J. Physiol. Lung Cell. Mol. Physiol. 310, L964-974. Hsp90 inhibition suppresses NF-κB transcriptional activation via Sirt-2 in human lung microvascular endothelial cells 2016

Thangjam, G. S., Birmpas, C., Barabutis, N., Gregory, B. W., Clemens, M. A., Newton, J. R. and Catravas, J. D. 


Notes: The authors of this study determined that Sirt-2 histone deacetylase binds human NF-κB target gene promoter. Sirt-2 prevents the recruitment of NF-κB proteins and subsequent assembly of RNA polymerase II complex in human lung microvascular endothelial cells. Sirt-2 activity was measured using SIRT-Glo™ Assay kit.  (4861)

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PLos ONE 11. Novel Roles of Epoxyeicosanoids in Regulating Cardiac Mitochondria. 2016

El-Sikhry, H. E., Alsaleh, N., Dakarapu, R., Falck, J. R. and Seubert, J. M.

Notes: In this study, researchers used the SIRT-Glo™ Assay to measure SIRT1 deacetylation activity.  (4864)

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Aging 8, 8. Scavengers of reactive γ-ketoaldehydes extend Caenorhabditis elegans lifespan and healthspan through protein-level interactions with SIR-2.1 and ETS-7 2016

Nguyen, T. T., Caito, S. W., Zackert, W. E., West, J. D., Zhu, S., Aschner, M. and Roberts, L. J. 

Notes: Researchers used the SIRT-Glo™ Assay and Screening System to measure the relative activity of the NAD+-dependent histone deacetylase (HDAC) class III enzymes (sirtuins). (4863)

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7, 124. SIRT Is Required for EDP-Mediated Protective Responses toward Hypoxia–Reoxygenation Injury in Cardiac Cells 2016

Samokhvalov, V., Jamieson, K. L., Fedotov, I., Endo, T., & Seubert, J. M.

Notes: The authors of this study examined the effects of EDPs on LPS-induced toxicity. They considered whether EDPs protect HL-1 cardiac cells from hypoxia-reoxygenation, via SIRT-1 associated preservation of mitochondrial quality. Sirtuins1 enzymatic activity was measured in the whole cell lysates by using SIRT-Glo™ Assay, and caspase 3/7 activity was assessed using the Apo-ONE™ Homogeneous Caspase-3/7 Assay. (4859)

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Mol. Cell 49, 474-486. Glucose-induced β-catenin acetylation enhances Wnt signaling in cancer.  2013

Chocarro-Calvo, A., García-Martínez, J. M., Ardila-González, S., De la Vieja, A. and García-Jiménez, C. 

Notes: Elevated blood glucose levels are largely associated with an increased risk for cancer, partially because of heightened insulin growth factor 1 signaling. The authors of this study examined glucose dependent β-catenin to determine whether elevated glucose directly impacts cancer-associated signal-transduction pathways. The SIRT-Glo™ Assay kit was used to measure SIRT1 activity.  (4860)

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