Larmuseau, M.H.D. et al.
Notes: The authors examined the usefulness of additional Y-STRs in distinguishing between unknown DNA donor and a database sample and for familial searching or estimating the geographical origin of the donor. They generated Y-STR haplotypes for 535 patrilineal-unrelated males from Flanders (Belgium). This geographic region was chosen because the Y-chromosomal variation and distribution are well characterized. By typing an additional 5 Y-STR loci (23 loci compared to 17), the authors were able to better discriminate between men with nearly identical Y-STR haplotypes, with a much lower number of uninformative Y-STR haplotype matches. A 23-locus haplotype was also more valuable for familial DNA searching and estimating the geographical origin of a DNA donor. (4505)