Orbach, S.M., Ehrich, M.F., and Rajagopalan, P.
Notes: These authors describe the design, assembly and toxicant response of multi-cellular 3D hepatic organotypic culture models. In high-throughput screening, changes in cell viability were determined over 24 hours using the RealTime-Glo™ MT Cell Viability Assay. Mechanism of cell death was determined with the ApoTox-Glo™ Triplex Assay, and GSH concentration was measured using the GSH-Glo™ Glutathione Assay. (5011)