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SLAS Discov 4, 366–377. Bioluminescent Assays for Glucose and Glutamine Metabolism: High-Throughput Screening for Changes in Extracellular and Intracellular Metabolites 2017

Leippe, D., Sobol, M., Vidugiris, G., Cali, J.J. and Vidugiriene, J.

Notes: The authors of this paper describe bioluminescent glucose, lactate, glutamine and glutamate assays suitable for high-throughput analysis of two major metabolic pathways in cancer cells: glycolysis and glutaminolysis. (4769)

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Biochim. Biophys. Acta 1863(12), 3254-3264. MDA-MB-231 breast cancer cells fuel osteoclast metabolism and activity: A new rationale for the pathogenesis of osteolytic bone metastases. 2017

Lemma, S., Di Pompo, G., Porporato, P.E., Sboarina, M., Russell, S., Gillies, R.J., Baldini, N., Sonveaux, P., and Avnet, S.

Notes: These authors showed that lactate released by glycolytic breast carcinoma cells in the bone microenvironment promotes the formation of osteolytic lesions. They used the Lactate-Glo™ and Glucose-Glo™ Assays to measure lactate and glucose in the medium of cultured cells over time. (5021)

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