ARHGEF15 overexpression worsens the prognosis in patients with pancreatic ductal adenocarcinoma through enhancing the motility and proliferative activity of the cancer cells.
Fukushima, H., Yasumoto, M., Ogasawara, S., Akiba, J., Kitasato, Y., Nakayama, M., Naito, Y., Ishida, Y., Okabe, Y., Yasunaga, M., Horiuchi, H., Sakamoto, E., Itadani, H., Mizuarai, S., Oie, S. and Yano, H.
Notes: Hs766T cells were transfected with a purchased HaloTag®-ARHGEF15 fusion expression vector in pFN21A and siRNA expression plasmids directed to the ARHGEF15 or nonsense sequence using the ViaFect™ Transfection Reagent (no details provided)., ARHGEF15 expression was visualized but the specific HaloTag® Ligand was not specified. (4667)
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