NanoBRET® Protein Interaction Assays

We have developed NanoBRET® Protein:Protein Interaction (PPI) Assays to measure the interaction of specific protein pairs for a variety of biological targets. Assays are available by direct order from our catalog or by custom order via quote. Click on the catalog number to visit the product catalog page or check the box next to assays of interest to submit an inquiry for more information.

  • RAS Signaling Collection

    Name
    BRAF/BRAF Dimer
    CRAF/CRAF Dimer
    HRasWT/CRAF FL or CRAF RBD
    KRasG12C/BRAF FL or BRAF RBD
    KRasG12D/ARAF FL or ARAF RBD
    KRasG12D/CRAF FL, CRAF RBD or CRAF RBD-CRD
    KRasG12V/BRAF FL or BRAF RBD
    KRasWT/ARAF FL or ARAF RBD
    KRasWT/CRAF FL, CRAF RBD or CRAF RBD-CRD
    NRasQ61K/CRAF FL or CRAF RBD
    NRasQ61R/CRAF FL or CRAF RBD
    NRasWT/CRAF FL or CRAF RBD
    Name
    BRAF/CRAF
    HRasWT/BRAF FL or BRAF RBD
    KRasG12C/ARAF FL or ARAF RBD
    KRasG12C/CRAF FL, CRAF RBD or CRAF RBD-CRD
    KRasG12D/BRAF or BRAF RBD
    KRasG12V/ARAF FL or ARAF RBD
    KRasG12V/CRAF FL, CRAF RBD or CRAF RBD-CRD
    KRasWT/BRAF FL or BRAF RBD
    NRasQ61K/BRAF FL or BRAF RBD
    NRasQ61R/BRAF FL or BRAF RBD
    NRasWT/BRAF FL or BRAF RBD
  • Signaling Proteins and Kinase Assays

    Name
    β-catenin/BCL9L
    β-catenin/TCF4
    ERK/ELK
    GADD45B/MKK7
    MEK/ERK
    MycN/AURKA
    SHN3/ERK2
    SKP2/CKS1B
    Name
    β-catenin/TCF3
    cMyc/AURKA
    FKBP/FRB
    MAVS/IFIH1
    MID1/Alpha4
    SHN3/ERK1
    SHN3/SHN3 Dimer
  • Other Epigenetic Assays

    Name
    CBX2/H3.1
    CBX7/Histone H3.2
    EZH2/SUZ12
    HDAC1/HDAC2
    MLL1/Menin
    PRMT5/RIOK1
    TUDOR/Histone H3.3
    Name
    CBX7/Histone H3.1
    CBX7/Histone H3.3
    FANCD2/Ubiquitin
    KDM4B/Histone H3.3
    MLL1/WDR5
    PRMT5/WDR77(MEP50)
  • Transcriptional Protein Assays

    NameCatalog #
    NanoBRET® cMyc/MAX Interaction AssayN1870
    NanoBRET® PPI Control Pair (p53/MDM2)N1641


    Name
    cMYc/WRD5
    FOXP3/FOXP3
    GR/GR (Dimerization)
    SP140/Histone H3.3
    TEAD1/YAP1
    TEAD2/YAP1
    TEAD3/YAP1
    TEAD4/YAP1
    Name
    ER/ER(Dimerization)
    FOXP3/NFATC2
    IRF5/IRF5 Dimer
    TEAD1/TAZ
    TEAD2/TAZ
    TEAD3/TAZ
    TEAD4/TAZ
  • Membrane Protein Assays

    Name
    DAP12/Syk
    GRB2/EGFR
    IL17RA/ACT1
    MERTK dimer
    Name
    DAP12/TREM2
    HCN1/TRIP8b
    MET/Grb2
    STIM1/Orai
  • Cellular Regulation

    Name
    ABHD5/PLIN5
    MCL-1/BIML
    Name
    CALR/MPL
    PNPLA3/ABHD5
  • Protein Degradation

    Name
    BRD4/CRBN
    Name
    E6/E6AP
  • Bromodomain Assays

    NameCatalog #
    NanoBRET® BRD 4/Histone H3.3 Interaction AssayN1830


    Name
    ATAD2/Histone H3.3
    BRD2/Histone H3.3
    BRD3/Histone H3.3
    BRD4 BD2/Histone H3.3
    BRD7 BD/Histone H3.3
    CBP/Histone H4
    SMARCA2/Histone H3.3
    Name
    ATAD2/Histone H4
    BRD2/Histone H4
    BRD3/Histone H4
    BRD4 BD2/Histone H4
    CBP/H3.3
    EP300 BD/Histone H4.4
Name
Address