SNAI1, snail family transcriptional repressor 1

SNAI1, snail family transcriptional repressor 1

• The Drosophila embryonic protein snail is a zinc finger transcriptional repressor which downregulates the expression of ectodermal genes within the mesoderm. The nuclear protein encoded by this gene is structurally similar to the Drosophila snail protein, and is also thought to be critical for mesoderm formation in the developing embryo. At least two variants of a similar processed pseudogene have been found on chromosome 2. [provided by RefSeq, Jul 2008]

• Gene Synonyms (zinc finger protein SNAI1, protein sna, protein snail homolog 1, snail 1 homolog, snail 1 zinc finger protein, snail family zinc finger 1, snail homolog 1, SLUGH2, SNA, SNAH, SNAIL, SNAIL1, dJ710H13.1,)
• NCBI Gene ID: 6615
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O95863
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

snail family transcriptional repressor 1 interacts with:

• 3-hydroxyacyl-CoA dehydratase 3
  activator of HSP90 ATPase activity 1
  adaptor related protein complex 3 subunit beta 2
  ajuba LIM protein
  ALG13 UDP-N-acetylglucosaminyltransferase subunit
  aminopeptidase puromycin sensitive
  apoptosis inducing factor mitochondria associated 1
  arginyl-tRNA synthetase 2, mitochondrial
  ataxin 10
  ATP binding cassette subfamily F member 2
  ATPase family AAA domain containing 3A
  ATPase family AAA domain containing 3B
  BAG cochaperone 2
  beta-transducin repeat containing E3 ubiquitin protein ligase
  biogenesis of ribosomes BRX1
  BRMS1 transcriptional repressor and anoikis regulator
  calcium homeostasis endoplasmic reticulum protein
  centrosomal protein 170
  centrosomal protein 70
  cerebellin 4 precursor
  chaperonin containing TCP1 subunit 2
  chaperonin containing TCP1 subunit 3
  chaperonin containing TCP1 subunit 4
  chaperonin containing TCP1 subunit 5
  chaperonin containing TCP1 subunit 7
  chaperonin containing TCP1 subunit 8
  clathrin heavy chain like 1
  cleavage and polyadenylation specific factor 6
  cleavage and polyadenylation specific factor 7
  component of oligomeric golgi complex 6
  coordinator of PRMT5 and differentiation stimulator
  COP9 signalosome subunit 5
  COPI coat complex subunit gamma 2
  CTD small phosphatase 1
  CTD small phosphatase 2
  CTD small phosphatase like
  cullin 1
  cullin associated and neddylation dissociated 1
  cytidine monophosphate N-acetylneuraminic acid synthetase
  DEAD-box helicase 17
  DEAD-box helicase 19A
  DEAD-box helicase 20
  death associated protein 3
  dedicator of cytokinesis 4
  DExD-box helicase 21
  DExD-box helicase 39A
  DExH-box helicase 30
  dipeptidyl peptidase 9
  DNA topoisomerase III alpha
  DnaJ heat shock protein family (Hsp40) member A3
  DnaJ heat shock protein family (Hsp40) member C10
  E2F transcription factor 7
  Ecm29 proteasome adaptor and scaffold
  EF-hand domain containing 1
  engulfment and cell motility 2
  enoyl-CoA delta isomerase 2
  ER lipid raft associated 2
  erythrocyte membrane protein band 4.1 like 3
  eukaryotic translation elongation factor 1 epsilon 1
  eukaryotic translation initiation factor 3 subunit F
  eukaryotic translation initiation factor 3 subunit G
  eukaryotic translation initiation factor 3 subunit L
  exosome component 4
  exosome component 8
  exportin 1
  exportin 5
  exportin for tRNA
  family with sequence similarity 98 member A
  F-box and leucine rich repeat protein 14
  F-box and leucine rich repeat protein 5
  F-box and leucine rich repeat protein 8
  F-box and WD repeat domain containing 7
  F-box protein 22
  F-box protein 31
  G protein nucleolar 3
  GAR1 ribonucleoprotein
  GCN1 activator of EIF2AK4
  gem nuclear organelle associated protein 4
  glomulin, FKBP associated protein
  glutamine rich 2
  glutaminyl-peptide cyclotransferase
  glutaminyl-peptide cyclotransferase like
  golgin A6 family like 9
  Gse1 coiled-coil protein
  H3 clustered histone 1
  H3.5 histone
  heat shock protein family H (Hsp110) member 1
  HECT and RLD domain containing E3 ubiquitin protein ligase 2
  heterogeneous nuclear ribonucleoprotein A3
  heterogeneous nuclear ribonucleoprotein R
  high mobility group 20A
  high mobility group 20B
  histone deacetylase 1
  histone deacetylase 2
  histone deacetylase 3
  hydroxysteroid 17-beta dehydrogenase 12
  importin 11
  importin 4
  importin 7
  importin 8
  importin 9
  influenza virus NS1A binding protein
  inner membrane mitochondrial protein
  insulin like growth factor 2 mRNA binding protein 1
  insulin like growth factor 2 mRNA binding protein 3
  insulin receptor substrate 4
  integrator complex subunit 4
  keratin 40
  keratin associated protein 10-3
  keratin associated protein 1-1
  KH RNA binding domain containing, signal transduction associated 1
  La ribonucleoprotein 1, translational regulator
  large tumor suppressor kinase 2
  lon peptidase 2, peroxisomal
  LSM14A mRNA processing body assembly factor
  LUC7 like 2, pre-mRNA splicing factor
  lysine demethylase 1A
  malignant fibrous histiocytoma amplified sequence 1
  MAP7 domain containing 1
  matrin 3
  methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like
  methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
  microtubule associated scaffold protein 2
  midline 2
  mitochondrial ribosomal protein S27
  mitochondrial ribosomal protein S31
  mitochondrial ribosomal protein S34
  mitogen-activated protein kinase kinase kinase 7
  MYB binding protein 1a
  neuralized E3 ubiquitin protein ligase 4
  nicotinamide phosphoribosyltransferase
  non-SMC condensin I complex subunit G
  notch 2 N-terminal like A
  nucleolar protein with MIF4G domain 1
  nucleoporin 205
  nucleoporin 93
  odr-4 GPCR localization factor homolog
  O-linked N-acetylglucosamine (GlcNAc) transferase
  ORC ubiquitin ligase 1
  OTU deubiquitinase, ubiquitin aldehyde binding 1
  paraspeckle component 1
  partner and localizer of BRCA2
  pelota mRNA surveillance and ribosome rescue factor
  pentatricopeptide repeat domain 3
  peptidylprolyl isomerase like 2
  peroxiredoxin 4
  peroxiredoxin 6
  phosphatidylinositol-4-phosphate 5-kinase type 1 beta
  phosphoglycerate dehydrogenase
  poly(A) binding protein cytoplasmic 1
  poly(A) binding protein cytoplasmic 4
  potassium channel tetramerization domain containing 5
  pre-mRNA processing factor 31
  pre-mRNA processing factor 6
  pre-mRNA processing factor 8
  prohibitin 2
  proteasome 26S subunit, non-ATPase 14
  proteasome 26S subunit, non-ATPase 6
  protein arginine methyltransferase 5
  RAB10, member RAS oncogene family
  RecQ mediated genome instability 1
  REST corepressor 1
  REST corepressor 3
  ribonuclease P/MRP subunit p30
  ribosomal protein L13a
  ribosomal protein L14
  RIO kinase 1
  RNA 2',3'-cyclic phosphate and 5'-OH ligase
  RNA 3'-terminal phosphate cyclase
  RNA binding motif protein 10
  RNA binding motif protein 17
  RNA binding motif protein 25
  RNA binding motif protein 5
  RNA binding motif protein X-linked
  RNA transcription, translation and transport factor
  Ro60, Y RNA binding protein
  RuvB like AAA ATPase 1
  RuvB like AAA ATPase 2
  Sad1 and UNC84 domain containing 2
  SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1
  SCY1 like pseudokinase 2
  serine/threonine kinase 11
  serine/threonine kinase 38
  serine/threonine kinase 38 like
  SIN3 transcription regulator family member A
  single stranded DNA binding protein 1
  sirtuin 2
  small nuclear ribonucleoprotein D1 polypeptide
  small nuclear ribonucleoprotein D2 polypeptide
  small nuclear ribonucleoprotein polypeptide A'
  small nuclear ribonucleoprotein polypeptide B2
  small nuclear ribonucleoprotein polypeptides B and B1
  small nuclear ribonucleoprotein U1 subunit 70
  small RNA binding exonuclease protection factor La
  snail family transcriptional repressor 1
  solute carrier family 25 member 11
  solute carrier family 25 member 13
  solute carrier family 25 member 24
  spectrin alpha, non-erythrocytic 1
  spindlin 1
  spindlin interactor and repressor of chromatin binding
  splicing factor 3b subunit 1
  splicing factor 3b subunit 2
  splicing factor 3b subunit 3
  STIP1 homology and U-box containing protein 1
  structural maintenance of chromosomes 1A
  structural maintenance of chromosomes 2
  structural maintenance of chromosomes 4
  SUZ12 polycomb repressive complex 2 subunit
  SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1
  synaptotagmin binding cytoplasmic RNA interacting protein
  t-complex 1
  tetratricopeptide repeat domain 25
  TGF-beta activated kinase 1 (MAP3K7) binding protein 1
  TGF-beta activated kinase 1 (MAP3K7) binding protein 2
  TGF-beta activated kinase 1 (MAP3K7) binding protein 3
  THO complex 3
  thyroid hormone receptor associated protein 3
  thyroid hormone receptor interactor 6
  TNF alpha induced protein 3
  TNF receptor associated factor 2
  trans-2,3-enoyl-CoA reductase
  transcriptional regulator, SIN3A (yeast)
  transforming growth factor beta 1
  transmembrane protein 263
  tripartite motif containing 21
  tripartite motif containing 50
  tRNA methyltransferase 10C, mitochondrial RNase P subunit
  Tu translation elongation factor, mitochondrial
  tubulin alpha 1a
  tubulin alpha 1b
  tubulin beta 2A class IIa
  tubulin beta 3 class III
  tubulin beta 4A class IVa
  tubulin beta 4B class IVb
  tubulin beta class I
  tumor protein p53
  twinkle mtDNA helicase
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta
  tyrosyl-tRNA synthetase 1
  U2 small nuclear RNA auxiliary factor 1
  U2 small nuclear RNA auxiliary factor 2
  U2 snRNP associated SURP domain containing
  ubiquinol-cytochrome c reductase core protein 2
  ubiquitin C
  ubiquitin specific peptidase 1
  ubiquitin specific peptidase 10
  ubiquitin specific peptidase 11
  ubiquitin specific peptidase 15
  ubiquitin specific peptidase 17 like family member 2
  ubiquitin specific peptidase 7
  voltage dependent anion channel 2
  voltage dependent anion channel 3
  WD repeat domain 26
  WD repeat domain 6
  WD repeat domain 77
  X-ray repair cross complementing 3
  Y-box binding protein 3

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.