ATXN10, ataxin 10

ATXN10, ataxin 10

• This gene encodes a protein that may function in neuron survival, neuron differentiation, and neuritogenesis. These roles may be carried out via activation of the mitogen-activated protein kinase cascade. Expansion of an ATTCT repeat from 9-32 copies to 800-4500 copies in an intronic region of this locus has been associated with spinocerebellar ataxia, type 10. Alternatively spliced transcript variants have been described.[provided by RefSeq, Jul 2016]

• Gene Synonyms (ataxin-10, brain protein E46 homolog, spinocerebellar ataxia type 10 protein, E46L, HUMEEP, SCA10,)
• NCBI Gene ID: 25814
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9UBB4
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

ataxin 10 interacts with:

• centromere protein J
  centrosomal protein 128
  coiled-coil domain containing 8
  cyclin dependent kinase 12
  dual specificity phosphatase 22
  egl-9 family hypoxia inducible factor 3
  GINS complex subunit 4
  glutathione S-transferase kappa 1
  golgi to ER traffic protein 4
  limb development membrane protein 1 like
  MAD2 mitotic arrest deficient-like 1
  mitochondrial ribosomal protein S16
  mitochondrial transcription termination factor 3
  myotubularin related protein 14
  pleckstrin homology domain containing A4
  protein tyrosine phosphatase mitochondrial 1
  serine/threonine/tyrosine interacting like 1
  sodium channel and clathrin linker 1
  transportin 1
  tubulin alpha 1c
  tubulin, gamma 1
  vir like m6A methyltransferase associated
  WW domain containing oxidoreductase

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.