RUVBL2, RuvB like AAA ATPase 2

RUVBL2, RuvB like AAA ATPase 2

• This gene encodes the second human homologue of the bacterial RuvB gene. Bacterial RuvB protein is a DNA helicase essential for homologous recombination and DNA double-strand break repair. Functional analysis showed that this gene product has both ATPase and DNA helicase activities. This gene is physically linked to the CGB/LHB gene cluster on chromosome 19q13.3, and is very close (55 nt) to the LHB gene, in the opposite orientation. [provided by RefSeq, Jul 2008]

• Gene Synonyms (CGI-46, ECP-51, ECP51, INO80J, REPTIN, RVB2, TAP54-beta, TIH2, TIP48, TIP49B, ruvB-like 2, 48 kDa TATA box-binding protein-interacting protein, 48 kDa TBP-interacting protein, 51 kDa erythrocyte cytosolic protein, INO80 complex subunit J, RuvB (E coli homolog)-like 2, TIP60-associated protein 54-beta, erythrocyte cytosolic protein, 51-KD, repressing pontin 52, reptin52 protein,)
• NCBI Gene ID: 10856
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9Y230
  UNIPROT ID#>>B3KNL2
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

RuvB like AAA ATPase 2 interacts with:

• AAR2 splicing factor
  actin like 6B
  actin related protein 5
  actin related protein 6
  actin related protein 8
  actin, beta
  adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1
  adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2
  argonaute RISC catalytic component 3
  autophagy related 16 like 1
  bromodomain containing 8
  calcium/calmodulin dependent protein kinase kinase 1
  cartilage acidic protein 1
  catenin beta interacting protein 1
  cell cycle and apoptosis regulator 2
  cell division cycle 73
  cereblon
  chromosome 12 open reading frame 45
  coiled-coil domain containing 103
  coiled-coil domain containing 8
  coiled-coil domain containing 87
  COPI coat complex subunit epsilon
  coronin 1B
  DEAD-box helicase 42
  decapping enzyme, scavenger
  deleted in primary ciliary dyskinesia homolog (mouse)
  derlin 1
  DNA methyltransferase 1 associated protein 1
  DnaJ heat shock protein family (Hsp40) member B4
  DnaJ heat shock protein family (Hsp40) member C17
  dynein cytoplasmic 2 heavy chain 1
  E1A binding protein p400
  E2F associated phosphoprotein
  EEF1A lysine methyltransferase 3
  enhancer of polycomb homolog 1
  enhancer of polycomb homolog 2
  euchromatic histone lysine methyltransferase 2
  expressed sequence AI837181
  F-box protein 25
  F-box protein 6
  F-box protein 7
  forkhead box R2
  glutamate rich WD repeat containing 1
  golgi phosphoprotein 3
  H2B clustered histone 1
  Holliday junction recognition protein
  importin 4
  inhibitor of growth family member 3
  INO80 complex ATPase subunit
  INO80 complex subunit B
  INO80 complex subunit C
  INO80 complex subunit D
  INO80 complex subunit E
  integrin alpha FG-GAP repeat containing 1
  interacts with SUPT6H, CTD assembly factor 1
  kinase suppressor of ras 1
  La ribonucleoprotein 7, transcriptional regulator
  leucine rich repeat kinase 2
  leucyl-tRNA synthetase 1
  ligand of numb-protein X 1
  mbt domain containing 1
  methylphosphate capping enzyme
  methyltransferase like 18
  methyltransferase like 3
  microcephalin 1
  MINDY lysine 48 deubiquitinase 4
  mitochondrial carrier 2
  mortality factor 4 like 1
  MRG domain binding protein
  multiple coagulation factor deficiency 2, ER cargo receptor complex subunit
  MYST/Esa1 associated factor 6
  NOP58 ribonucleoprotein
  nuclear FMR1 interacting protein 1
  nucleoside-triphosphatase, cancer-related
  obscurin like cytoskeletal adaptor 1
  p53 and DNA damage regulated 1
  PIH1 domain containing 1
  pleckstrin homology domain containing A4
  poly(rC) binding protein 3
  potassium channel tetramerization domain containing 15
  prefoldin 2
  pre-mRNA processing factor 8
  protein phosphatase 6 regulatory subunit 3
  RAD18 E3 ubiquitin protein ligase
  RAD52 motif containing 1
  receptor interacting serine/threonine kinase 4
  RIO kinase 1
  RNA polymerase I subunit A
  RNA polymerase II associated protein 2
  RNA polymerase II associated protein 3
  RNA polymerase III subunit A
  RNA polymerase III subunit E
  RPTOR independent companion of MTOR complex 2
  RuvB like AAA ATPase 2
  RuvB-like protein 1
  serine/arginine repetitive matrix 2
  serine/threonine kinase 40
  SHQ1, H/ACA ribonucleoprotein assembly factor
  sirtuin 6
  small nuclear ribonucleoprotein U5 subunit 200
  SMG1 nonsense mediated mRNA decay associated PI3K related kinase
  SNU13 homolog, small nuclear ribonucleoprotein (U4/U6.U5)
  SNW domain containing 1
  solute carrier family 7 member 6 opposite strand
  striatin 3
  SUMO specific peptidase 1
  SUMO specific peptidase 2
  SUMO specific peptidase 6
  SUZ12 polycomb repressive complex 2 subunit
  SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
  TAR DNA binding protein
  taxilin alpha
  TBC1 domain family member 7
  TCF3 fusion partner
  TELO2 interacting protein 2
  TNFAIP3 interacting protein 2
  transport and golgi organization 6 homolog
  tripartite motif containing 29
  tropomodulin 2
  tropomodulin 3
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
  ubiquilin 2
  ubiquitin C-terminal hydrolase L5
  UBX domain protein 6
  vir like m6A methyltransferase associated
  WAPL cohesin release factor
  WD repeat and coiled coil containing
  WD repeat domain 92
  WW domain containing E3 ubiquitin protein ligase 2
  zinc finger and BTB domain containing 38
  zinc finger and BTB domain containing 7A
  zinc finger protein 462

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.