ATG16L1, autophagy related 16 like 1

ATG16L1, autophagy related 16 like 1

• The protein encoded by this gene is part of a large protein complex that is necessary for autophagy, the major process by which intracellular components are targeted to lysosomes for degradation. Defects in this gene are a cause of susceptibility to inflammatory bowel disease type 10 (IBD10). Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jun 2010]

• Gene Synonyms (autophagy-related protein 16-1, APG16L beta, ATG16 autophagy related 16-like 1, WD repeat domain 30, APG16L, ATG16A, ATG16L, IBD10, WDR30,)
• NCBI Gene ID: 55054
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q53SV2
  UNIPROT ID#>>A0A024R494
  UNIPROT ID#>>A0A024R4B6
  UNIPROT ID#>>Q17RG0
  UNIPROT ID#>>Q676U5
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

autophagy related 16 like 1 interacts with:

• acylglycerol kinase
  ankyrin repeat domain 44
  apolipoprotein O like
  autophagy related 16 like 1
  autophagy related 16 like 2
  autophagy related 3
  autophagy related 9A
  axin interactor, dorsalization associated
  BRI3 binding protein
  bromodomain containing 9
  cactin, spliceosome C complex subunit
  caspase activity and apoptosis inhibitor 1
  catenin beta like 1
  CCR4-NOT transcription complex subunit 11
  CDK5 regulatory subunit associated protein 3
  CDKN2A interacting protein
  cell division cycle and apoptosis regulator 1
  cerebellin 4 precursor
  chromosome 1 open reading frame 35
  coiled-coil domain containing 12
  coiled-coil domain containing 124
  coiled-coil domain containing 43
  coiled-coil domain containing 47
  collectin subfamily member 12
  coronin 7
  CWC22 spliceosome associated protein homolog
  CWF19 like cell cycle control factor 1
  CWF19 like cell cycle control factor 2
  DDRGK domain containing 1
  DEAD-box helicase 54
  DEAD-box helicase 55
  death effector domain containing 2
  disco interacting protein 2 homolog B
  EF-hand domain family member D2
  epidermal growth factor receptor pathway substrate 15 like 1
  eukaryotic elongation factor, selenocysteine-tRNA specific
  eukaryotic translation initiation factor 2A
  eva-1 homolog A, regulator of programmed cell death
  exocyst complex component 4
  factor interacting with PAPOLA and CPSF1
  family with sequence similarity 133 member B
  family with sequence similarity 98 member B
  Fc receptor like A
  fermitin family member 3
  forty-two-three domain containing 1
  FtsJ RNA 2'-O-methyltransferase 3
  glutamate rich WD repeat containing 1
  H2A clustered histone 21
  helicase with zinc finger 2
  hydrogen voltage gated channel 1
  IKBKB interacting protein
  immunity related GTPase M
  ISY1 splicing factor homolog
  LanC like 2
  leucine rich repeats and calponin homology domain containing 3
  LIM domain containing 2
  LTV1 ribosome biogenesis factor
  mediator complex subunit 10
  mediator complex subunit 29
  mediator complex subunit 30
  mediator complex subunit 8
  methylphosphate capping enzyme
  microtubule associated monooxygenase, calponin and LIM domain containing 1
  microtubule associated protein 1 light chain 3 beta
  microtubule associated protein 1 light chain 3 gamma
  mitochondrial poly(A) polymerase
  mitochondrial ribosomal protein L14
  mitochondrial ribosomal protein S22
  mitochondrial ribosomal protein S9
  mitochondrial ribosome recycling factor
  NHP2 ribonucleoprotein
  nuclear assembly factor 1 ribonucleoprotein
  nuclear FMR1 interacting protein 2
  nuclear speckle splicing regulatory protein 1
  nucleotide binding oligomerization domain containing 2
  oxysterol binding protein like 8
  PCI domain containing 2
  PEST proteolytic signal containing nuclear protein
  peter pan homolog
  polypyrimidine tract binding protein 2
  potassium channel tetramerization domain containing 10
  proline rich coiled-coil 2B
  protein arginine methyltransferase 6
  protein arginine methyltransferase 8
  protein O-glucosyltransferase 2
  protein phosphatase 1 regulatory subunit 18
  protein phosphatase 1 regulatory subunit 9B
  RAB, member RAS oncogene family like 6
  RAB11 family interacting protein 1
  RAB33B, member RAS oncogene family
  Rho GTPase activating protein 15
  Rho GTPase activating protein 30
  ribosome binding factor A
  ribosome production factor 2 homolog
  ring finger protein 123
  RNA binding motif protein 26
  RNA binding motif protein 33
  RNA polymerase I subunit F
  RNA pseudouridine synthase D4
  SAFB like transcription modulator
  SAP domain containing ribonucleoprotein
  SDA1 domain containing 1
  SEH1 like nucleoporin
  selenoprotein H
  SET domain containing 7, histone lysine methyltransferase
  short coiled-coil protein
  sideroflexin 1
  sorting nexin 18
  SPC25 component of NDC80 kinetochore complex
  sperm antigen with calponin homology and coiled-coil domains 1
  splicing factor 3b subunit 5
  SRP receptor subunit beta
  SURP and G-patch domain containing 1
  synaptopodin 2
  tankyrase 2
  target of EGR1, exonuclease
  taxilin alpha
  terminal uridylyl transferase 7
  THO complex 3
  THO complex 6
  THO complex 7
  TRAF3 interacting protein 3
  transcription elongation factor A N-terminal and central domain containing 2
  transmembrane protein 74
  tripartite motif containing 56
  tubulin tyrosine ligase like 6
  WD repeat domain 18
  WD repeat domain 26
  WD repeat domain 33
  WD repeat domain 48
  WD repeat domain 70
  WD repeat domain 77
  WD repeat domain 83
  YLP motif containing 1
  YTH domain containing 1
  YTH domain containing 2
  zinc finger CCCH-type and G-patch domain containing
  zinc finger CCCH-type containing 14
  zinc finger CCCH-type containing, antiviral 1
  zinc finger CCHC-type containing 8

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.