SPECC1, sperm antigen with calponin homology and coiled-coil domains 1

SPECC1, sperm antigen with calponin homology and coiled-coil domains 1

• The protein encoded by this gene belongs to the cytospin-A family. It is localized in the nucleus, and highly expressed in testis and some cancer cell lines. A chromosomal translocation involving this gene and platelet-derived growth factor receptor, beta gene (PDGFRB) may be a cause of juvenile myelomonocytic leukemia. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]

• Gene Synonyms (cytospin-B, NSP5, cytokinesis and spindle organization B, nuclear structure protein 5, sperm antigen HCMOGT-1, sperm antigen with calponin-like and coiled coil domains 1, structure protein NSP5a3a, structure protein NSP5a3b, structure protein NSP5b3a, structure protein NSP5b3b, CYTSB, HCMOGT-1, HCMOGT1, NSP,)
• NCBI Gene ID: 92521
• Species: Homo sapiens (Human)
• UNIPROT ID#>>B4DW07
  UNIPROT ID#>>A0A024QYY9
  UNIPROT ID#>>Q5M775
  UNIPROT ID#>>B4E2A4
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

sperm antigen with calponin homology and coiled-coil domains 1 interacts with:

• filamin, beta
  myosin XVIIIA
  POC1 centriolar protein B
  solute carrier family 25 member 41
  tropomyosin 4

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.