THOC3, THO complex 3

THOC3, THO complex 3

• This gene encodes a component of the nuclear THO transcription elongation complex, which is part of the larger transcription export (TREX) complex that couples messenger RNA processing and export. In humans, the transcription export complex is recruited to the 5'-end of messenger RNAs in a splicing- and cap-dependent manner. Studies of a related complex in mouse suggest that the metazoan transcription export complex is involved in cell differentiation and development. A pseudogene of this gene has been defined on chromosome 5. [provided by RefSeq, May 2013]

• Gene Synonyms (THO complex subunit 3, TEX1 homolog, THO3, hTREX45,)
• NCBI Gene ID: 84321
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q96J01
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

THO complex 3 interacts with:

• egl-9 family hypoxia inducible factor 3
  kelch domain containing 9
  mixed lineage kinase domain like pseudokinase
  serine and arginine-rich splicing factor 1
  zinc finger CCHC-type and RNA binding motif containing 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.