AGO3, argonaute RISC catalytic component 3

AGO3, argonaute RISC catalytic component 3

• This gene encodes a member of the Argonaute family of proteins which play a role in RNA interference. The encoded protein is highly basic, contains a PAZ domain and a PIWI domain, and may play a role in short-interfering-RNA-mediated gene silencing. This gene is located on chromosome 1 in a tandem cluster of closely related family members including argonaute 4 and eukaryotic translation initiation factor 2C, 1. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

• Gene Synonyms (protein argonaute-3, argonaute 3, RISC catalytic component, eukaryotic translation initiation factor 2C, 3, hAgo3, EIF2C3,)
• NCBI Gene ID: 192669
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9H9G7
  UNIPROT ID#>>B4E1P5
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

argonaute RISC catalytic component 3 interacts with:

• argonaute RISC component 4
  ATPase H+ transporting V0 subunit d2
  tubulin beta class I

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.