BRD8, bromodomain containing 8

BRD8, bromodomain containing 8

• The protein encoded by this gene interacts with thyroid hormone receptor in a ligand-dependent manner and enhances thyroid hormone-dependent activation from thyroid response elements. This protein contains a bromodomain and is thought to be a nuclear receptor coactivator. Multiple alternatively spliced transcript variants that encode distinct isoforms have been identified. [provided by RefSeq, Jul 2014]

• Gene Synonyms (SMAP, SMAP2, p120, bromodomain-containing protein 8, skeletal muscle abundant protein 2, thyroid hormone receptor coactivating protein of 120 kDa, trCP120,)
• NCBI Gene ID: 10902
• Species: Homo sapiens (Human)
• UNIPROT ID#>>B4DMS9
  UNIPROT ID#>>Q9H0E9
  UNIPROT ID#>>B4DEG9
  UNIPROT ID#>>B4DN43
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

bromodomain containing 8 interacts with:

• checkpoint kinase 2
  cullin 9
  DNA methyltransferase 1 associated protein 1
  E1A binding protein p400
  enhancer of polycomb homolog 1
  fibronectin type III and SPRY domain containing 2
  forkhead box R1
  forkhead box R2
  H2B clustered histone 1
  inhibitor of growth family member 3
  mbt domain containing 1
  MIS18 kinetochore protein A
  mortality factor 4 like 1
  MRG domain binding protein
  MYST/Esa1 associated factor 6
  RuvB-like protein 1
  RuvB-like protein 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.